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Oncoimmunology. 2012 Dec 1;1(9):1648-1649.

Emerging evidence of anti-tumor immune control in the central nervous system.

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1
Department of Pediatrics; University of Colorado Anschutz Medical Campus and Children's Hospital; Colorado Center for Cancer and Blood Disorders; Aurora, CO USA.

Abstract

Microarray-based studies by our laboratory confirm that the immune control of tumor progression extends to the "immunoprivileged" central nervous system, identifying prognostic immune gene signatures in primary tumor specimens. Our results provide rationale and mechanistic insights for the development of immunotherapeutic strategies against brain tumors.

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