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Comp Med. 2012 Oct;62(5):439-42.

Intracranial meningioma with ophthalmoplegia in a rhesus macaque (Macaca mulatta).

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California National Primate Research Center, School of Veterinary Medicine, University of California Davis, Davis, California, USA.


A 21-y-old female rhesus macaque presented with signs of internal and external ophthamoplegia, including anisocoria and ptosis. Ophthalmoplegia is the paralysis or weakness of one or more intraocular or extraocular muscles that control the movement of eye; this condition can be caused by neurologic or muscle disorders. The macaque was euthanized due to progression of clinical symptoms, and postmortem gross examination revealed a mass at the base of the brain attached to the meninges. Histopathologic examination led to the diagnosis of intracranial meningioma. Here we describe a case of intracranial meningioma with internal and external ophthalmoplegia in a rhesus macaque (Macaca mulatta).

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