Format

Send to

Choose Destination
J Clin Microbiol. 2013 Jan;51(1):278-80. doi: 10.1128/JCM.02120-12. Epub 2012 Oct 10.

Evaluation of Clostridium difficile fecal load and limit of detection during a prospective comparison of two molecular tests, the illumigene C. difficile and Xpert C. difficile/Epi tests.

Author information

1
Department of Pathology and Laboratory Medicine, University of California, Davis, School of Medicine, Davis, California, USA.

Abstract

In a large prospective comparison, the illumigene test detected Clostridium difficile in 98% of toxin-positive and 58% of toxin-negative samples confirmed positive by other methods. The Xpert was uniformly sensitive. Most samples with discrepant results had C. difficile concentrations below the illumigene limit of detection. The significance of low-level C. difficile detection needs investigation.

PMID:
23052320
PMCID:
PMC3536201
DOI:
10.1128/JCM.02120-12
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center