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Clin Plast Surg. 2012 Oct;39(4):453-64. doi: 10.1016/j.cps.2012.07.014.

Adipocyte-derived stem and regenerative cells in facial rejuvenation.

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Division of Plastic and Reconstructive Surgery, Department of Surgery, University of California, 200 W. Arbor Drive, San Diego, CA 92103, USA.


The identification of regenerative cells in adult human fat has invigorated the field of facial fat grafting. This article reviews traditional and cell-enriched fat grafting methods and the use of fat to create or refine aesthetic results. The rationale and potential applications of adipocyte-derived stem and regenerative cells in facial surgery are also described. The reader is presented with surgical techniques for harvesting and delivering fat grafts to optimize engraftment. Mesotherapy and related applications currently under investigation are also discussed.

[Indexed for MEDLINE]

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