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Mamm Genome. 2012 Oct;23(9-10):632-40. doi: 10.1007/s00335-012-9427-x. Epub 2012 Sep 1.

The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.

Author information

1
MRC Mammalian Genetics Unit, MRC Harwell, Oxfordshire OX11 0RD, UK. s.brown@har.mrc.ac.uk

Abstract

Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.

PMID:
22940749
PMCID:
PMC3774932
DOI:
10.1007/s00335-012-9427-x
[Indexed for MEDLINE]
Free PMC Article

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