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Angew Chem Int Ed Engl. 2012 Jun 25;51(26):6416-20. doi: 10.1002/anie.201201443. Epub 2012 May 29.

Protein expression, aggregation, and triggered release from polymersomes as artificial cell-like structures.

Author information

1
The Division of Biomedical Engineering, School of Engineering, The University of Glasgow, Glasgow, G12 8LT, UK.

Abstract

Bringing droplets to life: A cytoskeletal protein (red dots, see scheme) is expressed in artificial cells composed of biocompatible polymersomes, which encapsulate expression machinery and amino acid building blocks. Release of the expressed proteins can be triggered by a negative osmotic shock.

PMID:
22644870
DOI:
10.1002/anie.201201443
[Indexed for MEDLINE]

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