Format

Send to

Choose Destination
Onkologie. 2012;35(4):200-2. doi: 10.1159/000337414. Epub 2012 Mar 15.

Peritoneal cystic mesothelioma: are surgery and HIPEC optimal first-line treatments?

Author information

1
Dept. of General and Emergency Surgery, Ospedali Riuniti, Bergamo, Italy. fedecocco@iol.it

Abstract

BACKGROUND:

Peritoneal cystic mesothelioma (PCM) is an uncommon clinical pathology. Its high rate of recurrence following partial or total resection as well as its spontaneous onset of malignancy have been well documented in a series of case studies. The medical community has yet to define standardized treatment guidelines for PCM.

CASE REPORTS:

This study reviews the case of 2 patients admitted and treated for PCM. Recent studies have reported improved recurrence and survival rates achieved by means of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), especially when used as first-line treatments. However, whether or not the use of CRS and HIPEC is more effective than a surgical regimen of multiple debulking procedures, is still the subject of debate.

CONCLUSION:

CRS and HIPEC as first-line treatments have lower morbidity and mortality rates than regimens of multiple back-to-back surgical procedures, and as such, the CRS/HIPEC method appears to be the more successful approach.

PMID:
22488091
DOI:
10.1159/000337414
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for S. Karger AG, Basel, Switzerland
Loading ...
Support Center