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RNA. 2012 Apr;18(4):605-9. doi: 10.1261/rna.032011.111. Epub 2012 Feb 17.

Another burst of smoke: atomic resolution structures of RF3 bound to the ribosome.

Author information

1
Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Abstract

Two recent reports provide atomic resolution information detailing the interaction of the class II release factor, RF3, with the bacterial ribosome. Differences in the composition of the two crystal forms allow us to learn a considerable amount about how translational GTPases engage the ribosome to facilitate and define conformational rearrangements involved in protein synthesis.

PMID:
22345149
PMCID:
PMC3312549
DOI:
10.1261/rna.032011.111
[Indexed for MEDLINE]
Free PMC Article

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