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Neuron. 2011 Jun 9;70(5):806-8. doi: 10.1016/j.neuron.2011.05.025.

Solving the autism puzzle a few pieces at a time.

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1
Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA. schaaf@bcm.edu

Erratum in

  • Neuron. 2011 Jul 14;71(1):195.

Abstract

In this issue, a pair of studies (Levy et al. and Sanders et al.) identify several de novo copy-number variants that together account for 5%-8% of cases of simplex autism spectrum disorders. These studies suggest that several hundreds of loci are likely to contribute to the complex genetic heterogeneity of this group of disorders. An accompanying study in this issue (Gilman et al.), presents network analysis implicating these CNVs in neural processes related to synapse development, axon targeting, and neuron motility.

PMID:
21658575
DOI:
10.1016/j.neuron.2011.05.025
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