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Front Biosci (Landmark Ed). 2011 Jun 1;16:2161-71.

The role of miRNAs in cytokine signaling.

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  • 1Monash Institute of Medical Research, Monash University, Clayton, Victoria 3168, Australia.


This review explores the relationship between cytokines and microRNAs (miRNAs). In particular, the regulation of miRNAs by pro-inflammatory cytokines, anti-inflammatory cytokines, interferons and transforming growth factor beta are examined, highlighting how miRNAs can mediate some of the known functions of these cytokines, as well as identifying novel gene targets, mechanisms and cross-talk between pathways.

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