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Curr Biol. 2011 Feb 22;21(4):R149-51. doi: 10.1016/j.cub.2011.01.018.

Asymmetric segregation: the shape of things to come?

Author information

1
Buck Institute for Research on Aging, Novato, CA 94945, USA. bkennedy@buckinstitute.org

Abstract

Yeast mother cells pay a sacrifice during budding: they keep the extrachromosomal rDNA circles (ERCs) so that their buds have a full lifespan ahead. Two new studies indicate that retention of ERCs in mother cells occurs not by tethering to the nuclear periphery but rather by the simple rules of diffusion in a time-limited and complex landscape.

PMID:
21334292
DOI:
10.1016/j.cub.2011.01.018
[Indexed for MEDLINE]
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