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Fertil Steril. 2010 Nov;94(6):2359-61. doi: 10.1016/j.fertnstert.2010.04.017.

Antioxidants, Oxyrase, and mitochondrial uncoupler 2,4-dinitrophenol improved postthaw survival of rhesus monkey sperm from ejaculates with low cryosurvival.

Author information

1
California National Primate Research Center, University of California, Davis, California 95616, USA.

Abstract

Various antioxidant strategies such as supplementation of antioxidants, limiting oxygen concentration with Oxyrase, and reducing reactive oxygen species through mild mitochondrial uncoupling had statistically significant beneficial effects on sperm cryopreservation from rhesus monkeys with low cryoresistant ejaculates. Individuals or species that have higher sensitivity to cryodamage may derive the most benefit from these treatments.

PMID:
20553783
PMCID:
PMC4201370
DOI:
10.1016/j.fertnstert.2010.04.017
[Indexed for MEDLINE]
Free PMC Article

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