Extensive comedonal and cystic acne in Patau syndrome

Pediatr Dermatol. 2010 Mar-Apr;27(2):199-200. doi: 10.1111/j.1525-1470.2010.01098.x.

Abstract

Patau syndrome is a chromosomal disorder associated with multiple malformations caused by inheritance of an extra chromosome (trisomy 13). Some skin defects have been reported in patients with Patau syndrome, such as scalp defects, glabellar stains, deep palmar creases, rocker-bottom feet, convex soles, hyperconvextity of the nails, and multiple hemangiomas. To our knowledge, widespread comedonal and cystic acne have not been previously reported in Patau syndrome.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / diagnosis*
  • Abnormalities, Multiple / genetics
  • Abscess / diagnosis*
  • Abscess / drug therapy
  • Abscess / genetics
  • Acne Vulgaris / diagnosis*
  • Acne Vulgaris / drug therapy
  • Acne Vulgaris / genetics
  • Benzoyl Peroxide / therapeutic use
  • Chromosomes, Human, Pair 13 / genetics
  • Clindamycin / therapeutic use
  • Erythromycin / therapeutic use
  • Face*
  • Female
  • Humans
  • Infant
  • Retinoids / therapeutic use
  • Sebaceous Glands / abnormalities
  • Syndrome
  • Trisomy / diagnosis*
  • Trisomy / genetics

Substances

  • Retinoids
  • Clindamycin
  • Erythromycin
  • Benzoyl Peroxide