Format

Send to

Choose Destination

See 1 citation found using an alternative search:

Clin J Am Soc Nephrol. 2014 Mar;9(3):600-8. doi: 10.2215/CJN.06410613. Epub 2014 Jan 9.

Update on membranoproliferative GN.

Author information

1
Division of Nephrology, Winthrop University Hospital, Mineola, New York, †Division of Kidney Diseases and Hypertension, Hofstra North Shore-Long Island Jewish School of Medicine, Great Neck, New York.

Abstract

Membranoproliferative GN represents a pattern of injury seen on light microscopy. Historically, findings on electron microscopy have been used to further subclassify this pathologic entity. Recent advances in understanding of the underlying pathobiology have led to a proposed classification scheme based on immunofluorescence findings. Dysregulation of the complement system has been shown to be a major risk factor for the development of a membranoproliferative GN pattern of injury on kidney biopsy. Evaluation and treatment of this complex disorder rest on defining the underlying mechanisms.

PMID:
24408117
PMCID:
PMC3944764
DOI:
10.2215/CJN.06410613
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center