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Nephrol Dial Transplant. 2003 Aug;18 Suppl 6:vi52-8.

Secondary minimal change disease.

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The Geffen School of Medicine at UCLA, California, USA.


The great majority of patients identified as having a 'minimal change lesion' accompanying the nephrotic syndrome have a primary or 'idiopathic' disorder. Nevertheless, it is quite apparent that a similar or identical lesion can appear consequent to a growing number of underlying diseases; it is then known as 'secondary minimal change disease'. The predisposing conditions include neoplastic diseases, toxic or allergic reactions to drugs, infections, auto-immune disorders and other miscellaneous entities. These disorders are reviewed and catalogued in this contribution.

[Indexed for MEDLINE]

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