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1924 2
1928 1
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1940 1
1942 1
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1977 2045
1978 1997
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1980 1977
1981 2068
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2000 2725
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2005 3476
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2012 5226
2013 5277
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The following term was not found in PubMed: 2-Methyl-4-heptafluoroisopropyl
Page 1
N-Acetyl-4-aminophenol (paracetamol), N-acetyl-2-aminophenol and acetanilide in urine samples from the general population, individuals exposed to aniline and paracetamol users.
Dierkes G, Weiss T, Modick H, Käfferlein HU, Brüning T, Koch HM. Dierkes G, et al. Int J Hyg Environ Health. 2014 Apr-May;217(4-5):592-9. doi: 10.1016/j.ijheh.2013.11.005. Epub 2013 Dec 6. Int J Hyg Environ Health. 2014. PMID: 24370547
We applied this method to three sets of urine samples: (1) individuals with no known exposure to aniline and also no recent paracetamol medication; (2) individuals after occupational exposure to aniline but no paracetamol medication and (3) paracetamol users. ...In …
We applied this method to three sets of urine samples: (1) individuals with no known exposure to aniline and also no recent paracetam …
Differences in Pharmacokinetics and Haematotoxicities of Aniline and Its Dimethyl Derivatives Orally Administered in Rats.
Miura T, Kamiya Y, Murayama N, Shimizu M, Yamazaki H. Miura T, et al. Biol Pharm Bull. 2021 Nov 1;44(11):1775-1780. doi: 10.1248/bpb.b21-00589. Epub 2021 Aug 26. Biol Pharm Bull. 2021. PMID: 34433705 Free article.
Aniline and its dimethyl derivatives reportedly become haematotoxic after metabolic N-hydroxylation of their amino groups. ...These results suggest that rapid and extensive metabolic activation of aniline and its dimethyl derivatives occurred in rats and that the pr …
Aniline and its dimethyl derivatives reportedly become haematotoxic after metabolic N-hydroxylation of their amino groups. ...These r …
Production of Multiple Talaroenamines from Penicillium malacosphaerulum via One-Pot/Two-Stage Precursor-Directed Biosynthesis.
Zhang Z, He X, Zhang X, Li D, Wu G, Liu Z, Niu C, Yang L, Song W, Li Z, Wang Z. Zhang Z, et al. J Nat Prod. 2022 Sep 23;85(9):2168-2176. doi: 10.1021/acs.jnatprod.2c00394. Epub 2022 Aug 22. J Nat Prod. 2022. PMID: 35993848 Review.
During this approach, the initial precursor p-methylaniline was first used as a carrier to capture the biologically synthesized cyclohexanedione to produce talaroenamine F, and then the other aniline derivatives were employed to replace the p-methylaniline fragment of tala …
During this approach, the initial precursor p-methylaniline was first used as a carrier to capture the biologically synthesized cyclohexaned …
Construction of Benzoxazinones from Anilines and Their Derivatives.
Zhao TF, Xu XL, Sun WY, Lu Y. Zhao TF, et al. Org Lett. 2023 Jul 14;25(27):4968-4973. doi: 10.1021/acs.orglett.3c01511. Epub 2023 Jul 3. Org Lett. 2023. PMID: 37395616
Herein we report a strategy concerning Rh(III)-catalyzed direct ortho-C-H bond carbonylation to construct benzoxazinones from anilines and their derivatives with high atom economy. Interestingly, the corresponding amides were generated in situ from anilines when exc …
Herein we report a strategy concerning Rh(III)-catalyzed direct ortho-C-H bond carbonylation to construct benzoxazinones from anilines …
Kinetic Target-Guided Synthesis of Small-Molecule G-Quadruplex Stabilizers.
Pomeislová A, Vrzal L, Kozák J, Dobiaš J, Hubálek M, Dvořáková H, Reyes-Gutiérrez PE, Teplý F, Veverka V. Pomeislová A, et al. ChemistryOpen. 2020 Dec 3;9(12):1236-1250. doi: 10.1002/open.202000261. eCollection 2020 Dec. ChemistryOpen. 2020. PMID: 33304739 Free PMC article.
Accordingly, G-quadruplex stabilization by a suitable ligand may be a viable approach for anticancer therapy. In our study, we used the 4-(4-methylpiperazin-1-yl)aniline molecule, previously identified as a fragment library screen hit, as a template for the SAR-guided desi …
Accordingly, G-quadruplex stabilization by a suitable ligand may be a viable approach for anticancer therapy. In our study, we used the 4-(4 …
Conductive poly(2,5-substituted aniline)s highly soluble both in water and organic solvents.
Xu S, Ogi S, Sugiyasu K, Sumi S, Kobayashi Y, Takeuchi M. Xu S, et al. J Nanosci Nanotechnol. 2014 Jun;14(6):4449-54. doi: 10.1166/jnn.2014.8280. J Nanosci Nanotechnol. 2014. PMID: 24738411
Highly soluble conductive polyanilines were synthesized from newly designed aniline derivatives: 2,5-bis(2-methoxyethoxy)aniline (2) and 2,5-bis[2-(2-methoxyethoxy)ethoxy]aniline (3). ...The length of ethylene-1,2-dioxy chains on the polyaniline scarcely affe …
Highly soluble conductive polyanilines were synthesized from newly designed aniline derivatives: 2,5-bis(2-methoxyethoxy)aniline …
C-H chlorination of (hetero)anilines via photo/organo co-catalysis.
Xie W, Wang M, Yang S, Chen Y, Feng J, Huang Y. Xie W, et al. Org Biomol Chem. 2022 Jul 6;20(26):5319-5324. doi: 10.1039/d2ob00834c. Org Biomol Chem. 2022. PMID: 35730736
Chlorinated (hetero)anilines are a class of important structural motifs that are widely present in synthetic building blocks and pharmaceuticals. Despite recent advancements, direct aniline chlorination still suffers from ortho/para and mono/poly chlorination select …
Chlorinated (hetero)anilines are a class of important structural motifs that are widely present in synthetic building blocks and phar …
2-Substituted Aniline as a Simple Scaffold for LuxR-Regulated QS Modulation.
Li S, Wawrzyniak J, Queneau Y, Soulère L. Li S, et al. Molecules. 2017 Nov 29;22(12):2090. doi: 10.3390/molecules22122090. Molecules. 2017. PMID: 29186042 Free PMC article.
The ability of the 2-substituted aniline motif to serve as a scaffold for designing potential LuxR-regulated quorum sensing (QS) modulators has been investigated, using docking experiments and biological evaluation of a series of 15 specially synthesized compounds. …
The ability of the 2-substituted aniline motif to serve as a scaffold for designing potential LuxR-regulated quorum sensing (QS) modu …
Catalyst-Free Decarboxylative Amination of Carboxylic Acids in Water Microdroplets.
Meng Y, Gnanamani E, Zare RN. Meng Y, et al. J Am Chem Soc. 2023 Jan 11;145(1):32-36. doi: 10.1021/jacs.2c12236. Epub 2022 Dec 25. J Am Chem Soc. 2023. PMID: 36566437
We report the use of in situ generated hydroxyl radicals to carry out an organic transformation in one step, namely, the formation of anilines from aryl acids as well as both ammonia and primary/secondary amines via decarboxylation. ...Hydrolysis followed by liberation of …
We report the use of in situ generated hydroxyl radicals to carry out an organic transformation in one step, namely, the formation of ani …
Iodine-mediated one-pot intramolecular decarboxylation domino reaction for accessing functionalised 2-(1,3,4-oxadiazol-2-yl)anilines with carbonic anhydrase inhibitory action.
Angapelly S, Ramya PVS, Sodhi R, Angeli A, Rangan K, Nagesh N, Supuran CT, Arifuddin M. Angapelly S, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):615-628. doi: 10.1080/14756366.2018.1443447. J Enzyme Inhib Med Chem. 2018. PMID: 29536768 Free PMC article.
A practical and transition metal-free one-pot domino synthesis of diversified (1,3,4-oxadiazol-2-yl)anilines has been developed employing isatins and hydrazides as the starting materials, in the presence of molecular iodine. ...Most of the compounds exhibited low mi …
A practical and transition metal-free one-pot domino synthesis of diversified (1,3,4-oxadiazol-2-yl)anilines has been developed emplo …
180,957 results
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