Aneurysmal bone cyst at C2: imaging evaluation after intralesional injection of calcitonin and methylprednisolone

Arq Neuropsiquiatr. 2008 Sep;66(3B):711-5. doi: 10.1590/s0004-282x2008000500020.

Abstract

Objective: To demonstrate imaging findings during the follow-up of patients with aneurysmal bone cyst (ABC) of C2 treated with intralesional injection of calcitonin and methylprednisolone.

Method: Three patients with ABC of C2 were treated percutaneously with intralesional injection of calcitonin and methylprednisolone. All the patients were females, with ages varying from 6 to 13 years. All of them presented with cervical masses, but without neurological symptoms.

Results: Imaging follow-up with CT and plain films showed progressive ossification and reduction of the blood-filled cavities with volume reduction of all lesions. No recurrence was noted during the follow-up.

Conclusion: Intralesional injection of calcitonin and methylprednisolone is a safe treatment option for cervical ABC. The CT scan is especially valuable as a guide of injection site and for the follow-up of ossification of the treated ABCs.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Inflammatory Agents / administration & dosage*
  • Bone Cysts, Aneurysmal / diagnostic imaging
  • Bone Cysts, Aneurysmal / drug therapy*
  • Bone Density Conservation Agents / administration & dosage*
  • Calcitonin / administration & dosage*
  • Cervical Vertebrae* / diagnostic imaging
  • Child
  • Drug Therapy, Combination
  • Female
  • Humans
  • Injections, Intralesional
  • Methylprednisolone / administration & dosage*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Bone Density Conservation Agents
  • Calcitonin
  • Methylprednisolone