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Enferm Infecc Microbiol Clin. 2008 Jun-Jul;26(6):338-42.

[Benefits of Affirm VPIII and L-PAP in the diagnosis of bacterial vaginosis].

[Article in Spanish]

Author information

1
División de Investigación y Enseñanza, Hospital Juárez de México, Colonia Magdalena de las Salinas, México.

Abstract

INTRODUCTION:

Bacterial vaginosis is a syndrome occurring in women of reproductive age, characterized by abnormal vaginal discharge and associated with gynecological and obstetric problems during pregnancy.

AIM:

This study assesses the value of proline aminopeptidase (L-Pap) detection and DNA hybridization with the Affirm VPIII microbial identification test, as analytical tools for the diagnosis of bacterial vaginosis.

MATERIAL AND METHODS:

Vaginal secretions from 406 women were collected and analyzed to investigate bacterial vaginosis with the Affirm VPIII commercial kit and the L-Pap reaction. The criteria of Nugent et al, and Amsel et al. were used to characterize patients with bacterial vaginosis syndrome. Results were analyzed with a 2 x 2 contingency table and evaluated by the chi-square test, at a significance level of P < 0.05.

RESULTS:

L-Pap showed a sensitivity of 92.2%, specificity of 93.4%, PPV of 91.7% and NPV of 93.8%. The Affirm VPIII method had a sensitivity of 91.1%, specificity of 94.7%, PPV of 93.1% and NPV of 93.8%. The diagnostic performance of the two tests showed no statistical differences. CONCLUSION. L-Pap and Affirm VPIII are both suitable tests for fast, accurate diagnosis of bacterial vaginosis.

PMID:
18588815
[Indexed for MEDLINE]

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