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Gynecol Endocrinol. 2007 Jan;23(1):34-7.

Dysgerminoma of the ovary with precocious puberty: a case report.

Author information

1
Department of Obstetrics and Gynecology, Inha University School of Medicine, Incheon, South Korea.

Abstract

Ovarian dysgerminoma is usually hormonally inert, but when it contains syncytiotrophoblastic giant cells or undergoes malignant transformation, the level of estradiol might be elevated. A 6-year-old girl contracted ovarian dysgerminoma with precocious puberty, and her levels of beta-human chorionic gondaotropin, alpha-fetoprotein and estradiol were high. After resection of the tumor, levels of tumor markers became normal and precocious puberty disappeared. We report this unusual type of dysgerminoma with a brief review of the literature.

PMID:
17484510
DOI:
10.1080/09513590601095111
[Indexed for MEDLINE]

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