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Curr Biol. 2007 Feb 20;17(4):R136-9.

Ribosomal translocation: LepA does it backwards.

Author information

1
Howard Hughes Medical Institute, Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.

Abstract

During translation, mRNA is threaded through the ribosome in precise and directional three-nucleotide steps. A recent paper identifies a new GTPase, LepA, which catalyzes unexpected one-codon backward movement on the ribosome.

PMID:
17307049
DOI:
10.1016/j.cub.2006.12.029
[Indexed for MEDLINE]
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