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J Clin Immunol. 2005 Nov;25(6):503-10.

Innate sensors of microbial infection.

Author information

1
HHMI and Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA. diana.hargreaves@yale.edu

Abstract

The innate immune system utilizes multiple families of pattern-recognition receptors (PRRs) to protect the host from infection. Each of these families contributes certain elements to the complement of innate effector functions that is elicited during an infection. Here we review the families of PRRs and explore examples of their cooperativity.

PMID:
16380814
DOI:
10.1007/s10875-005-8065-4
[Indexed for MEDLINE]

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