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J Clin Rheumatol. 2005 Dec;11(6):323-5.

Ochronotic arthropathy: disappearance of alkaptonuria after liver transplantation for hepatitis B-related cirrhosis.

Author information

1
Department of Medicine, Section of Gastroenterology and Hepatology, Ege University, School of Medicine, Bornova, Izmir, Turkey. arzukobak@yahoo.com

Abstract

The deficiency of homogentisic acid oxidase, an enzyme that is mainly found in hepatocytes, is associated with alkaptonuria and ochronosis. We report a patient with clinical and radiologic findings of ochronotic arthropathy in whom alkaptonuria disappeared and the progressive course of the disease stopped after liver transplantation for hepatitis B-related cirrhosis.

PMID:
16371803
[Indexed for MEDLINE]

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