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Bioinformatics. 2005 Dec 1;21(23):4309-11. Epub 2005 Sep 27.

HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients.

Author information

1
Department of Mathematics, Imperial College London, UK. g.montana@imperial.ac.uk

Abstract

We have developed a simulation tool HapSim for the generation of haplotype data. The simulated haplotypes are such that their allele frequencies and linkage disequilibrium coefficients match exactly those estimated in a real sample.

AVAILABILITY:

The program is available as an R package and can be downloaded from http://cran.r-project.org/.

PMID:
16188927
DOI:
10.1093/bioinformatics/bti689
[Indexed for MEDLINE]

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