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Int J Gynaecol Obstet. 2004 Dec;87(3):267-71.

Conducting international collaborative research in developing nations.

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Department of Obstetrics and Gynecology, University of Illinois at Chicago, Chicago, IL 60612, USA.


International research partnerships bring together some of the best and the brightest in an effort to tackle global health problems. Such collaborations also pose complex challenges, such as maintaining ethical principles in the conduct of research in developing nations. In implementing a randomized clinical trial to reduce postpartum hemorrhage (PPH) during childbirth in rural India, U.S. and Indian collaborators addressed three such issues: the appropriateness of an ethical randomized controlled trial in the developing world, the inclusion of a placebo arm, and the relevance of informed consent in a semiliterate rural population.

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