Format

Send to

Choose Destination
Science. 2004 Oct 1;306(5693):79-86.

The genome of the diatom Thalassiosira pseudonana: ecology, evolution, and metabolism.

Author information

1
School of Oceanography, University of Washington, Seattle, WA 98195, USA. armbrust@ocean.washington.edu

Abstract

Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are responsible for approximately 20% of global carbon fixation. We report the 34 million-base pair draft nuclear genome of the marine diatom Thalassiosira pseudonana and its 129 thousand-base pair plastid and 44 thousand-base pair mitochondrial genomes. Sequence and optical restriction mapping revealed 24 diploid nuclear chromosomes. We identified novel genes for silicic acid transport and formation of silica-based cell walls, high-affinity iron uptake, biosynthetic enzymes for several types of polyunsaturated fatty acids, use of a range of nitrogenous compounds, and a complete urea cycle, all attributes that allow diatoms to prosper in aquatic environments.

PMID:
15459382
DOI:
10.1126/science.1101156
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire
Loading ...
Support Center