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Phys Rev Lett. 2004 Jul 30;93(5):058101. Epub 2004 Jul 26.

Unpinning and removal of a rotating wave in cardiac muscle.

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Institut Non Linéaire de Nice, 1361 route des Lucioles, F-06560 Valbonne, France.


Rotating waves in cardiac muscle may be pinned to a heterogeneity, as it happens in superconductors or in superfluids. We show that the physics of electric field distribution between cardiac cells permits one to deliver an electric pulse exactly to the core of a pinned wave, without knowing its position, and even to locations where a direct access is not possible. Thus, unpinning or removal of rotating waves can be achieved. The energy needed is 2 orders of magnitude less than defibrillation energy. This opens a way to new manipulations with pinned vortices both in experiments and in cardiac clinics.

[Indexed for MEDLINE]

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