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Presse Med. 2003 Oct 4;32(32):1505-6.

[Upper mesenteric venous thrombosis revealing familial resistance to activated protein C].

[Article in French]

Author information

1
Service d'anesthésie-réanimation, Hôpital du Val de Grâce, Paris. GRIMS@caramail.com

Abstract

INTRODUCTION:

Mesenteric venous thrombosis is a rare disease but potentially severe because of the prognosis of intestinal infarction with high mortality rate (60%).

OBSERVATION:

We report the case of a 55 year-old man who presented with an upper mesenteric venous thrombosis related to a familial resistance to C reactive protein through factor V Leiden mutation.

COMMENTS:

The discovery of a mesenteric venous thrombosis requires aetiological research that is usually multifactorial. Among the most frequent genetic coagulation abnormalities observed resistance to C reactive protein due to G202110A prothrombin gene mutation is the most common. Although factor V Leiden mutation is less frequent, it requires anticoagulation therapy for life in the case of the appearance of a thrombosis.

PMID:
14534468
[Indexed for MEDLINE]

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