Complex karyotype in a low grade phyllodes tumor of the breast

Cancer Genet Cytogenet. 2002 Jan 15;132(2):149-51. doi: 10.1016/s0165-4608(01)00536-2.

Abstract

Cytogenetic analysis of a phyllodes tumor of low grade malignancy disclosed the karyotype 52-55,XX, -1,+5,+7,+9,+10,+11,-15,+18,-19,+20,der(21)t(1;21)(p13;q22),+mar1x 2-4,+mar2[cp18]/46,XX. This study shows that a complex chromosome karyotype can be found in low-grade phyllodes tumors and is not necessarily a sign of extreme malignancy of these neoplasms.

Publication types

  • Case Reports

MeSH terms

  • Biopsy
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology
  • Female
  • Humans
  • Karyotyping
  • Middle Aged
  • Phyllodes Tumor / genetics*
  • Phyllodes Tumor / pathology