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Dement Geriatr Cogn Disord. 1999;10 Suppl 1:85-7.

Role of oxidative stress in frontotemporal dementia.

Author information

1
Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.

Abstract

Recent reports have established oxidative stress and damage as playing a role in the pathogenesis of a number of neurodegenerative diseases including Alzheimer disease, Parkinson disease, corticobasal degeneration, Pick's disease and Alexander's disease. Here we present evidence that oxidative damage is also one of the earliest cytopathological markers of neuronal dysfunction in frontotemporal dementia.

PMID:
10436348
DOI:
10.1159/000051220
[Indexed for MEDLINE]

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