Myocarditis: somethings old and something new

Cardiovasc Pathol. 2020 Jan-Feb:44:107155. doi: 10.1016/j.carpath.2019.107155. Epub 2019 Oct 10.

Abstract

"Since the pathological conditions take place at the cellular level, viral myocarditis and postinfectious autoimmunity can be suggested but not diagnosed clinically. All clinical methods including imaging techniques are misleading if infectious agents are involved. Accurate diagnosis demands simultaneous histologic, immunohistochemical, and molecular biological workup of the tissue. If the primary infectious or immune-mediated causes of the disease are carefully defined by clinical and biopsy-based tools, specific antiviral treatment options in addition to basic symptomatic therapy are available under certain conditions. These may allow a tailored cause-specific treatment that improves symptoms and prognosis of patients with acute and chronic disease." Uwe Kühl; Heinz-Peter SchultheissViral myocarditis.Swiss Medical Weekly. 144():w14010, JAN 2014 DOI:10.4414/smw.2014.14010.

Keywords: Cardiomyopathy; Cardiovascular pathology; Myocarditis.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases / immunology
  • Autoimmune Diseases / pathology*
  • Autoimmune Diseases / therapy
  • Autoimmunity
  • Biopsy
  • Cardiomyopathies / immunology
  • Cardiomyopathies / pathology*
  • Cardiomyopathies / therapy
  • Cardiomyopathies / virology
  • Host-Pathogen Interactions
  • Humans
  • Myocarditis / epidemiology
  • Myocarditis / pathology*
  • Myocarditis / therapy
  • Myocarditis / virology
  • Myocardium / immunology
  • Myocardium / pathology*
  • Predictive Value of Tests
  • Prognosis
  • Risk Factors
  • Virus Diseases / immunology
  • Virus Diseases / pathology*
  • Virus Diseases / therapy
  • Virus Diseases / virology