Format

Send to

Choose Destination
Rev Esp Enferm Dig. 2019 Nov 22;112. doi: 10.17235/reed.2019.6441/2019. [Epub ahead of print]

Clinical validation of Endofaster® for a rapid diagnosis of Helicobacter pylori infection.

Author information

1
Digestivo, Hospital Universitario Ramón y Cajal, España.
2
Gastroenterología y Hepatología, Hospital Universitario Ramón y Cajal, España.
3
Anatomía Patológica, Hospital Universitario Ramón y Cajal, España.
4
Gastroenterología, Hospital Universitario Ramón y Cajal, España.

Abstract

BACKGROUND:

this study aimed to evaluate the diagnostic accuracy of the Endofaster® for the detection of Helicobacter pylori.

METHODS:

during upper gastrointestinal endoscopy, gastric juice was aspirated to perform an analysis using the Endofaster®. This test was considered as positive when the ammonium concentration was > 67 ppm, negative when < 57 ppm and weakly positive between 57 and 67. Biopsy specimens were also taken as the gold standard.

RESULTS:

among the 86 patients enrolled in the study, the Endofaster® result was positive in 23.7%, negative in 54.7% and weakly positive in 11.6%, whereas infection was detected via histology in 38.4% of patients. The accuracy was 81.4%, with a Kappa value of 0.57.

CONCLUSIONS:

the Endofaster® could be useful to perform a rapid diagnosis of Helicobacter pylori infection (area under the curve = 0.81).

PMID:
31755285
DOI:
10.17235/reed.2019.6441/2019
Free full text

Supplemental Content

Full text links

Icon for Aran ediciones, S.L.
Loading ...
Support Center