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Rev Esp Enferm Dig. 2019 Mar 4;111. doi: 10.17235/reed.2019.5915/2018. [Epub ahead of print]

A long-term prospective study of the efficacy and safety of endoscopic septotomy using the LigaSure® system for the treatment of Zenker's diverticulum.

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Endoscopia Digestiva, Hospital Universitari i Politecnic la Fe, Spain.
Unidad de Endoscopia Digestiva, Hospital Universitario Politécnico la Fe, España.
Hospital Universitario y Politécnico la Fe.
Unidad de Endoscopia Digestiva, Hospital Universitario y Politécnico La Fe, España.



endoscopic septotomy of the cricopharyngeal muscle (ESCM) is a technique used for the treatment of Zenker's diverticulum (ZD). The experience with computerized vascular sealing systems (LigaSure® type) is limited. The objective of this study was to evaluate the efficacy and safety of ESCM using LigaSure®.


this was a long-term prospective study of 18 patients with ZD, who were referred to our hospital due to ESCM between 2010 and 2016. The severity of the symptoms was determined using the Dakkak-Bennett validated scale for dysphagia and the rest with numerical scales. The rates of relapse and retreatment were evaluated.


ESCM with LigaSure® was performed in 17 cases, one case was excluded due to technical difficulties. The median age was 72 years and regurgitation, dysphagia and respiratory symptoms were found in 100%, 89% and 56% of cases, respectively. The median size of the diverticulum was 28 mm (20-60 mm). The median time of the procedure was 35 minutes (25-45 minutes). There were four complications, two hemorrhages and two perforations. The median follow-up was 13 months (range: 12-82 months). Clinical improvements were observed for all symptoms and were maintained 12 months after treatment (p < 0.05). There was no relapse during follow-up in 13 patients. A complete section was not achieved and clinical relapse occurred after a median time of seven months that required retreatment in the remaining patients.


ESCM with LigaSure® may be a safe and effective technique in long-term follow-up situations, with low rates of relapse.

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