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Parasite. 2020;27:14. doi: 10.1051/parasite/2020011. Epub 2020 Mar 13.

Update on Cryptosporidium spp.: highlights from the Seventh International Giardia and Cryptosporidium Conference.

Author information

1
Department of Infectious Disease & Global Health, Cummings School of Veterinary Medicine at Tufts University, North Grafton, 01536 MA, USA.
2
Spanish National Centre for Microbiology, 28220 Majadahonda, Spain.
3
Institute of Parasitology, Biology Centre CAS, 370 05 České Budějovice, Czech Republic - Faculty of Agriculture, University of South Bohemia in České Budějovice, 370 05 České Budějovice, Czech Republic.
4
Cryptosporidium Reference Unit, Public Health Wales, SA2 8QA Swansea, UK - Swansea Medical School, Swansea University, SA2 8PP Swansea, UK.
5
Center for Tropical and Emerging Global Diseases, Institute of Bioinformatics and Department of Genetics, University of Georgia, Athens, 30602 GA, USA.
6
College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642 Guangdong, PR China.
7
Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, 380 South University Avenue, Philadelphia, 19104 PA, USA.
8
INRAE, Université François Rabelais de Tours, Centre Val de Loire, ISP, Laboratoire Apicomplexes et Immunité Mucosale, 37380 Nouzilly, France.
9
French National Cryptosporidiosis Reference Center, Rouen University Hospital, 1 Rue de Germont, 76031 Rouen Cedex, France - EA 7510, UFR Santé, University of Rouen Normandy, Normandy University, 22 Bd. Gambetta, 76183 Rouen Cedex, France.

Abstract

in English, French

While cryptosporidiosis is recognized as being among the most common causes of human parasitic diarrhea in the world, there is currently limited knowledge on Cryptosporidium infection mechanisms, incomplete codification of diagnostic methods, and a need for additional therapeutic options. In response, the Seventh International Giardia and Cryptosporidium Conference (IGCC 2019) was hosted from 23 to 26 June 2019, at the Rouen Normandy University, France. This trusted event brought together an international delegation of researchers to synthesize recent advances and identify key research questions and knowledge gaps. The program of the interdisciplinary conference included all aspects of host-parasite relationships from basic research to applications to human and veterinary medicine, and environmental issues associated with waterborne parasites and their epidemiological consequences. In relation to Cryptosporidium and cryptosporidiosis, the primary research areas for which novel findings and the most impressive communications were presented and discussed included: Cryptosporidium in environmental waters, seafood, and fresh produce; Animal epidemiology; Human cryptosporidiosis and epidemiology; Genomes and genomic evolution encompassing: Comparative genomics of Cryptosporidium spp., Genomic insights into biology, Acquiring and utilizing genome sequences, Genetic manipulation; Host-parasite interaction (immunology, microbiome); and Diagnosis and treatment. High quality presentations discussed at the conference reflected decisive progress and identified new opportunities that will engage investigators and funding agencies to spur future research in a "one health" approach to improve basic knowledge and the clinical and public health management of zoonotic cryptosporidiosis.

KEYWORDS:

Cryptosporidiosis; Cryptosporidium; Epidemiology; Genomics

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