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Rev Bras Ortop. 2018 Apr 5;53(3):384-388. doi: 10.1016/j.rboe.2018.03.014. eCollection 2018 May-Jun.

Primary angiosarcoma of the femur in a patient with Takayasu arteritis.

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Hospital AC Camargo Cancer Center, São Paulo, SP, Brazil.


in English, Portuguese

Primary osseous angiosarcoma is a rare entity with variable biological behavior and poor prognosis. Little is known about the oncologic treatment and its etiology is still unknown. This study presents a case of lytic lesion in the right femur with dissemination to other bones, such as the vertebral column and skull, and to the lungs and central nervous system. Orthopedic surgery was performed in order to improve quality of life. Surgical specimen confirmed the diagnosis of high-grade malignant osseous angiosarcoma. Despite oncologic and orthopedic treatment, the patient had rapid and aggressive progression with a poor outcome.


Bone neoplasm; Metastatic neoplasm; Primary angiosarcoma; Takayasu arteritis

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