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Adv Mater. 2018 Jun;30(23):e1707495. doi: 10.1002/adma.201707495. Epub 2018 Apr 25.

3D Printed Functional and Biological Materials on Moving Freeform Surfaces.

Author information

1
Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
2
Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN, 55455, USA.
3
Center for Genome Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
4
Stem Cell Institute, Department of Pediatrics, University of Minnesota, Minneapolis, MN, 55455, USA.
5
Asan-Minnesota Institute for Innovating Transplantation, University of Minnesota, Minneapolis, MN, 55455, USA.

Abstract

Conventional 3D printing technologies typically rely on open-loop, calibrate-then-print operation procedures. An alternative approach is adaptive 3D printing, which is a closed-loop method that combines real-time feedback control and direct ink writing of functional materials in order to fabricate devices on moving freeform surfaces. Here, it is demonstrated that the changes of states in the 3D printing workspace in terms of the geometries and motions of target surfaces can be perceived by an integrated robotic system aided by computer vision. A hybrid fabrication procedure combining 3D printing of electrical connects with automatic pick-and-placing of surface-mounted electronic components yields functional electronic devices on a free-moving human hand. Using this same approach, cell-laden hydrogels are also printed on live mice, creating a model for future studies of wound-healing diseases. This adaptive 3D printing method may lead to new forms of smart manufacturing technologies for directly printed wearable devices on the body and for advanced medical treatments.

KEYWORDS:

3D printing; bioprinting; feedback control; robotics; wireless electronics

PMID:
29691902
PMCID:
PMC6310159
[Available on 2019-06-01]
DOI:
10.1002/adma.201707495

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