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Cancer Med. 2018 May;7(5):2101-2108. doi: 10.1002/cam4.1347. Epub 2018 Mar 24.

Epidemiology of multiple myeloma in 17 Latin American countries: an update.

Author information

1
Epidemiology and Statistics Group, Research Center, A.C Camargo Cancer Center, São Paulo, Brazil.
2
International Prevention Research Institute, Ecully, France.
3
National Institute for Science and Technology in Oncogenomics and Therapeutic Innovation, Brazil.
4
Graduate Program in Public Health, School of Public Health, University of São Paulo, São Paulo, Brazil.
5
Collective Health Department, Federal University of Rio Grande do Norte, Natal, Brazil.

Abstract

The objective of this study was to describe incidence, mortality rates, and trends for multiple myeloma (MM) in Latin America (LA), contributing to better knowledge on the epidemiology of MM in this continent. Incidence data were extracted from the International Agency for Research on Cancer (IARC), for the period 1990-2007. Mortality data were obtained for 17 countries from the World Health Organization, for the period 1995-2013. Annual average percentage change (AAPC) and 95% confidence interval (95% CI) were calculated for incidence and mortality. The average incidence rate of MM was higher in Cali (Colombia). For the age-group over 60 years old, rates were 14.2 and 12.8 per 100,000 inhabitants for men and women, respectively. Increasing incidence trends were verified for Cali (Colombia). Mortality rates were higher among men; most countries presented increasing trends, and the highest increments were observed in Guatemala (12.5% [95% CI: 10.6; 14.5] in men; 8.8% [95% CI: 7.8; 9.8] in women), Ecuador (5.5% [95% CI: 5.0; 6.0] in men; 3.7 [95% CI: 3.1; 4.3] in women), Paraguay (2.9% [95% CI: 2.3; 3.5] in men; 3.2% [95% CI: 2.1; 4.3] in women), and Brazil (1.4% [95% CI: 1.3; 1.5] in men; 0.9% [95% CI: 0.8; 1.0] in women). Multiple myeloma presented heterogeneous incidence patterns in Cali (Colombia), Quito (Ecuador), and Costa Rica. Increasing mortality trends were verified for most Latin American countries and could be related to limited access to diagnosis and new therapies.

KEYWORDS:

incidence; mortality; multiple myeloma; trend

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