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The following term was not found in PubMed: 1-Boc-4-
Page 1
Kinetics and mechanisms of the reactions of 3-methoxyphenyl, 3-chlorophenyl, and 4-cyanophenyl 4-nitrophenyl thionocarbonates with alicyclic amines.
Castro EA, Leandro L, Quesieh N, Santos JG. Castro EA, et al. J Org Chem. 2001 Sep 7;66(18):6130-5. doi: 10.1021/jo0157371. J Org Chem. 2001. PMID: 11529741
The reactions of 3-methoxyphenyl, 3-chlorophenyl, and 4-cyanophenyl 4-nitrophenyl thionocarbonates (1, 2, and 3, respectively) with a series of secondary alicyclic amines are studied kinetically in 44 wt % ethanol-water at 25.0 degrees C and an ionic strength of 0.2 …
The reactions of 3-methoxyphenyl, 3-chlorophenyl, and 4-cyanophenyl 4-nitrophenyl thionocarbonates (1, 2, and 3, respectively) …
The sigma-selective ligand NE-100 attenuates the effect of phencyclidine in a rat diving model.
Ogawa S, Okuyama S, Tsuchida K, Araki H, Otomo S. Ogawa S, et al. Gen Pharmacol. 1995 Jan;26(1):177-82. doi: 10.1016/0306-3623(94)00151-c. Gen Pharmacol. 1995. PMID: 7713358
The serotonin2 (5-HT2) antagonist, ritanserin, and the sigma receptor ligands, 1-(cyclopropylmethyl)-4-[2'(4"-fluorophenyl)-2'-oxoethyl]- piperidine HBr (Dup734), 4-[2'-(4"-cyanophenyl)-2'-oxoethyl]-1- (cyclopropylmethyl)piperidine (XJ448), alpha-(4-fluorophenyl)-4- …
The serotonin2 (5-HT2) antagonist, ritanserin, and the sigma receptor ligands, 1-(cyclopropylmethyl)-4-[2'(4"-fluorophenyl)-2'-oxoethyl]- pi …
Potent and selective inhibitors of platelet-derived growth factor receptor phosphorylation. 3. Replacement of quinazoline moiety and improvement of metabolic polymorphism of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.
Matsuno K, Ushiki J, Seishi T, Ichimura M, Giese NA, Yu JC, Takahashi S, Oda S, Nomoto Y. Matsuno K, et al. J Med Chem. 2003 Nov 6;46(23):4910-25. doi: 10.1021/jm020505v. J Med Chem. 2003. PMID: 14584942
Novel selective antagonist radioligands for the pharmacological study of A(2B) adenosine receptors.
Gessi S, Varani K, Merighi S, Leung E, Mac Lennan S, Baraldi PG, Borea PA. Gessi S, et al. Purinergic Signal. 2006 Nov;2(4):583-8. doi: 10.1007/s11302-006-9019-x. Epub 2006 Jul 8. Purinergic Signal. 2006. PMID: 18404460 Free PMC article.
Recently, high-affinity radioligands for A(2B) receptors, [N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)-phenoxy]acetamide ([(3)H]MRS 1754), N-(2-(2-Phenyl-6-[4-(2,2,3,3-tetratritrio-3-phenylpropyl)-piperazine-1-carbonyl]-7H …
Recently, high-affinity radioligands for A(2B) receptors, [N-(4-cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1 …
Kinetic and mechanistic investigation of the aminolysis of 3-methoxyphenyl 3-nitrophenyl thionocarbonate, 3-chlorophenyl 3-nitrophenyl thionocarbonate, and bis(3-nitrophenyl) thionocarbonate.
Castro EA, Galvez A, Leandro L, Santos JG. Castro EA, et al. J Org Chem. 2002 Jun 14;67(12):4309-15. doi: 10.1021/jo025562a. J Org Chem. 2002. PMID: 12054968
Reactions of substrates 6 and 7 with piperidine and of thionocarbonate 8 with the same amine and piperazine, 1-(2-hydroxyethyl)piperazine, and morpholine show linear k(obsd) vs [amine] plots, with slopes (k(1)) independent of pH. ...The k(1) values for the aminolysi …
Reactions of substrates 6 and 7 with piperidine and of thionocarbonate 8 with the same amine and piperazine, 1-(2-hydroxyethyl)pip …
Effect of NE-100, a novel sigma receptor ligand, on phencyclidine-induced cognitive dysfunction.
Ogawa S, Okuyama S, Araki H, Otomo S. Ogawa S, et al. Eur J Pharmacol. 1994 Sep 22;263(1-2):9-15. doi: 10.1016/0014-2999(94)90517-7. Eur J Pharmacol. 1994. PMID: 7821367
NE-100 significantly shortened the PCP-induced prolonged swimming latency as did 1-(cyclopropylmethyl)-4-[2'(4"-fluorophenyl)-2'-oxoethyl]- piperidine monohydrobromide (Dup 734), 4-[2'-(4"-cyanophenyl)-2'-oxoethyl]-1-(cyclopropyl-methyl)pi peridine (XJ 448), alpha-( …
NE-100 significantly shortened the PCP-induced prolonged swimming latency as did 1-(cyclopropylmethyl)-4-[2'(4"-fluorophenyl)-2'-oxoethyl]- …
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
McBriar MD, Guzik H, Shapiro S, Paruchova J, Xu R, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'neill K, Spar BD, Weig B, Weston DJ, Farley C, Cook J. McBriar MD, et al. J Med Chem. 2006 Apr 6;49(7):2294-310. doi: 10.1021/jm050886n. J Med Chem. 2006. PMID: 16570926