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Page 1
Cimetidine disrupts the renewal of testicular cells and the steroidogenesis in a hermaphrodite fish.
García-García M, Liarte S, Gómez-González NE, García-Alcázar A, Pérez-Sánchez J, Meseguer J, Mulero V, García-Ayala A, Chaves-Pozo E. García-García M, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2016 Nov;189:44-53. doi: 10.1016/j.cbpc.2016.07.004. Epub 2016 Jul 27. Comp Biochem Physiol C Toxicol Pharmacol. 2016. PMID: 27475025
The importance of histamine in the physiology of the testis in mammals and reptiles has been recently shown. Histamine receptors (Hrs) are well conserved in fish and are functional in several fish species. ...Our data point to cimetidine as a reproductive disruptor …
The importance of histamine in the physiology of the testis in mammals and reptiles has been recently shown. Histamine receptors (Hrs …
The use of a salmonella bacteriophage in bearded dragons: application, passage time and reisolation.
Renfert K, Rabsch W, Fruth A, Speck S, Pees M. Renfert K, et al. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2019 Aug;47(4):247-256. doi: 10.1055/a-0959-5528. Epub 2019 Aug 21. Tierarztl Prax Ausg K Kleintiere Heimtiere. 2019. PMID: 31434125 English.
The pH tolerance of the phage was tested and drugs were used to evaluate their influence on the gastric pH of the reptiles. After pH adjustment, the phage was administered orally for 12 consecutive days. ...CONCLUSION AND CLINICAL RELEVANCE: The study provides first result …
The pH tolerance of the phage was tested and drugs were used to evaluate their influence on the gastric pH of the reptiles. After pH …
Kallikrein-kinin system in the plasma of the snake Bothrops jararaca.
Abdalla FM, Hiraichi E, Picarelli ZP, Prezoto BC. Abdalla FM, et al. Br J Pharmacol. 1989 Sep;98(1):252-8. doi: 10.1111/j.1476-5381.1989.tb16889.x. Br J Pharmacol. 1989. PMID: 2804549 Free PMC article.
This effect was tachyphylactic and was potentiated by captopril, a kininase II inhibitor; it was partially antagonized by promethazine plus cimetidine and was not affected by atropine. 2. Similar hypotensive effects were obtained by administration of trypsin or a partially …
This effect was tachyphylactic and was potentiated by captopril, a kininase II inhibitor; it was partially antagonized by promethazine plus …
Characterization of organic cation transport by avian renal brush-border membrane vesicles.
Villalobos AR, Braun EJ. Villalobos AR, et al. Am J Physiol. 1995 Nov;269(5 Pt 2):R1050-9. doi: 10.1152/ajpregu.1995.269.5.R1050. Am J Physiol. 1995. PMID: 7503291
Studies on perfused tubules and isolated membranes from mammals and reptiles have demonstrated that organic cations (OC) are transported across the luminal (brush-border) membrane by OC/H+ exchange. ...TEA transport could be indirectly coupled to sodium transport. Unlabele …
Studies on perfused tubules and isolated membranes from mammals and reptiles have demonstrated that organic cations (OC) are transpor …
Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved.
Galvão Nascimento N, Sampaio MC, Amaral Olivo R, Teixeira C. Galvão Nascimento N, et al. Toxicon. 2010 Feb-Mar;55(2-3):343-52. doi: 10.1016/j.toxicon.2009.08.009. Epub 2009 Aug 22. Toxicon. 2010. PMID: 19703484 Free article.
Intraperitoneal BmV injection (2.5-10 microg/site) induced MCs degranulation and release of PGD(2). Treatment with promethazine, cimetidine or thioperamide, histamine H1, H2 and H3/H4 receptor antagonists, respectively, markedly reduced the initial phase of oedema. ...
Intraperitoneal BmV injection (2.5-10 microg/site) induced MCs degranulation and release of PGD(2). Treatment with promethazine, cimetidi
Presynaptic inhibition of primary olfactory afferents mediated by different mechanisms in lobster and turtle.
Wachowiak M, Cohen LB. Wachowiak M, et al. J Neurosci. 1999 Oct 15;19(20):8808-17. doi: 10.1523/JNEUROSCI.19-20-08808.1999. J Neurosci. 1999. PMID: 10516300 Free PMC article.
In the lobster, application of the inhibitory transmitters GABA or histamine suppressed action potentials in the terminals. The suppression was blocked by picrotoxin and cimetidine, respective antagonists to lobster GABA and histamine receptors. ...
In the lobster, application of the inhibitory transmitters GABA or histamine suppressed action potentials in the terminals. The suppression …
Pharmacological study of edema induced by venom of the snake Bothrops asper (terciopelo) in mice.
Chaves F, Barboza M, Gutiérrez JM. Chaves F, et al. Toxicon. 1995 Jan;33(1):31-9. doi: 10.1016/0041-0101(94)00135-u. Toxicon. 1995. PMID: 7778127
However, no inhibitory effect was observed when mice were pretreated with verapamil, nordihydroguaiaretic acid, pyrilamine, cimetidine and propranolol. When drugs were administered after venom injection, only prazosin and indomethacin were effective in reducing edema. ...
However, no inhibitory effect was observed when mice were pretreated with verapamil, nordihydroguaiaretic acid, pyrilamine, cimetidine
Influence of species, sex and drug pretreatment on the metabolism of metyrapone.
Dixon PA, Okereke SE, Enwelum MC. Dixon PA, et al. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;81(1):241-3. doi: 10.1016/0742-8413(85)90122-7. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985. PMID: 2861055
Anthracene did not affect metyrapone N-oxides formation in the male rat; however phenobarbitone and pregnenolone significantly induced N-oxide II formation, whereas ethanol induced both isomeric N-oxides formation. Cimetidine, a known cytochrome P-450 inhibitor, inhibited …
Anthracene did not affect metyrapone N-oxides formation in the male rat; however phenobarbitone and pregnenolone significantly induced N-oxi …
Effect of adenosine 5'triphosphate (ATP) on the isolated rectum of the rainbow lizard Agama agama.
Savage AO, Atanga GK. Savage AO, et al. Gen Pharmacol. 1985;16(3):235-40. doi: 10.1016/0306-3623(85)90075-8. Gen Pharmacol. 1985. PMID: 4018537
Theophylline, quinidine, nifedipine and lack of Ca2+ inhibited ATP contractions, but dipyridamole, indomethacin, atropine, D-tubocurarine, phentolamine, L-propranolol, cimetidine, mepyramine and methysergide did not significantly modify the contractions. ...
Theophylline, quinidine, nifedipine and lack of Ca2+ inhibited ATP contractions, but dipyridamole, indomethacin, atropine, D-tubocurarine, p …