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Items: 1 to 20 of 37

1.

Npas4 Transcription Factor Expression Is Regulated by Calcium Signaling Pathways and Prevents Tacrolimus-induced Cytotoxicity in Pancreatic Beta Cells.

Speckmann T, Sabatini PV, Nian C, Smith RG, Lynn FC.

J Biol Chem. 2016 Feb 5;291(6):2682-95. doi: 10.1074/jbc.M115.704098. Epub 2015 Dec 9.

2.

Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation.

Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, Han J, Fan Y, Lynn FC, Trucco M, Borchers CH, Foster LJ, Nislow C, Kieffer TJ, Johnson JD.

Cell Metab. 2016 Jan 12;23(1):179-93. doi: 10.1016/j.cmet.2015.10.016. Epub 2015 Nov 25.

3.

Use-dependent activation of neuronal Kv1.2 channel complexes.

Baronas VA, McGuinness BR, Brigidi GS, Gomm Kolisko RN, Vilin YY, Kim RY, Lynn FC, Bamji SX, Yang R, Kurata HT.

J Neurosci. 2015 Feb 25;35(8):3515-24. doi: 10.1523/JNEUROSCI.4518-13.2015.

4.

SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models.

Xu EE, Krentz NA, Tan S, Chow SZ, Tang M, Nian C, Lynn FC.

Diabetologia. 2015 May;58(5):1013-23. doi: 10.1007/s00125-015-3507-x. Epub 2015 Feb 5.

PMID:
25652387
5.

All-encomPASsing regulation of β-cells: PAS domain proteins in β-cell dysfunction and diabetes.

Sabatini PV, Lynn FC.

Trends Endocrinol Metab. 2015 Jan;26(1):49-57. doi: 10.1016/j.tem.2014.11.002. Epub 2014 Dec 11. Review.

PMID:
25500169
6.

TALEN/CRISPR-mediated eGFP knock-in add-on at the OCT4 locus does not impact differentiation of human embryonic stem cells towards endoderm.

Krentz NA, Nian C, Lynn FC.

PLoS One. 2014 Dec 4;9(12):e114275. doi: 10.1371/journal.pone.0114275. eCollection 2014.

7.

Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes.

Chow SZ, Speck M, Yoganathan P, Nackiewicz D, Hansen AM, Ladefoged M, Rabe B, Rose-John S, Voshol PJ, Lynn FC, Herrera PL, Müller W, Ellingsgaard H, Ehses JA.

Diabetes. 2014 Sep;63(9):2984-95. doi: 10.2337/db13-1121. Epub 2014 May 8.

8.

Quetiapine treatment in youth is associated with decreased insulin secretion.

Ngai YF, Sabatini P, Nguyen D, Davidson J, Chanoine JP, Devlin AM, Lynn FC, Panagiotopoulos C.

J Clin Psychopharmacol. 2014 Jun;34(3):359-64. doi: 10.1097/JCP.0000000000000118.

PMID:
24633003
9.

Characterization of polyhormonal insulin-producing cells derived in vitro from human embryonic stem cells.

Bruin JE, Erener S, Vela J, Hu X, Johnson JD, Kurata HT, Lynn FC, Piret JM, Asadi A, Rezania A, Kieffer TJ.

Stem Cell Res. 2014 Jan;12(1):194-208. doi: 10.1016/j.scr.2013.10.003. Epub 2013 Oct 16.

10.

The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development.

Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML.

J Biol Chem. 2013 Aug 23;288(34):24429-40. doi: 10.1074/jbc.M113.463083. Epub 2013 Jul 8.

11.

Npas4 is a novel activity-regulated cytoprotective factor in pancreatic β-cells.

Sabatini PV, Krentz NA, Zarrouki B, Westwell-Roper CY, Nian C, Uy RA, Shapiro AM, Poitout V, Lynn FC.

Diabetes. 2013 Aug;62(8):2808-20. doi: 10.2337/db12-1527. Epub 2013 May 8.

12.

Identification and analysis of murine pancreatic islet enhancers.

Tennant BR, Robertson AG, Kramer M, Li L, Zhang X, Beach M, Thiessen N, Chiu R, Mungall K, Whiting CJ, Sabatini PV, Kim A, Gottardo R, Marra MA, Lynn FC, Jones SJ, Hoodless PA, Hoffman BG.

Diabetologia. 2013 Mar;56(3):542-52. doi: 10.1007/s00125-012-2797-5. Epub 2012 Dec 14.

13.

Maintenance of β-cell maturity and plasticity in the adult pancreas: developmental biology concepts in adult physiology.

Szabat M, Lynn FC, Hoffman BG, Kieffer TJ, Allan DW, Johnson JD.

Diabetes. 2012 Jun;61(6):1365-71. doi: 10.2337/db11-1361. Review. No abstract available.

14.

Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization.

Whitaker GM, Lynn FC, McIntosh CH, Accili EA.

PLoS One. 2012;7(3):e32675. doi: 10.1371/journal.pone.0032675. Epub 2012 Mar 7.

15.

Sequence and epigenetic determinants in the regulation of the Math6 gene by Neurogenin3.

Pujadas G, Felipe F, Ejarque M, Sanchez L, Cervantes S, Lynn FC, Gomis R, Gasa R.

Differentiation. 2011 Sep;82(2):66-76. doi: 10.1016/j.diff.2011.05.006. Epub 2011 Jun 14.

PMID:
21676531
16.

A mouse model for monitoring islet cell genesis and developing therapies for diabetes.

Shimajiri Y, Kosaka Y, Scheel DW, Lynn FC, Kishimoto N, Wang J, Zhao S, German MS.

Dis Model Mech. 2011 Mar;4(2):268-76. doi: 10.1242/dmm.002998. Epub 2010 Dec 6.

17.

Serotonin regulates pancreatic beta cell mass during pregnancy.

Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H, Fujitani Y, Kawamori R, Miyatsuka T, Kosaka Y, Yang K, Honig G, van der Hart M, Kishimoto N, Wang J, Yagihashi S, Tecott LH, Watada H, German MS.

Nat Med. 2010 Jul;16(7):804-8. doi: 10.1038/nm.2173. Epub 2010 Jun 27.

18.

Rfx6 directs islet formation and insulin production in mice and humans.

Smith SB, Qu HQ, Taleb N, Kishimoto NY, Scheel DW, Lu Y, Patch AM, Grabs R, Wang J, Lynn FC, Miyatsuka T, Mitchell J, Seerke R, Désir J, Vanden Eijnden S, Abramowicz M, Kacet N, Weill J, Renard ME, Gentile M, Hansen I, Dewar K, Hattersley AT, Wang R, Wilson ME, Johnson JD, Polychronakos C, German MS.

Nature. 2010 Feb 11;463(7282):775-80. doi: 10.1038/nature08748.

19.

Meta-regulation: microRNA regulation of glucose and lipid metabolism.

Lynn FC.

Trends Endocrinol Metab. 2009 Nov;20(9):452-9. doi: 10.1016/j.tem.2009.05.007. Epub 2009 Sep 30. Review.

PMID:
19800254
20.

Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors.

Wang YC, Gallego-Arteche E, Iezza G, Yuan X, Matli MR, Choo SP, Zuraek MB, Gogia R, Lynn FC, German MS, Bergsland EK, Donner DB, Warren RS, Nakakura EK.

Endocr Relat Cancer. 2009 Mar;16(1):267-79. doi: 10.1677/ERC-08-0127. Epub 2008 Nov 5.

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