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Items: 1 to 20 of 42


Multiscale modeling of layer formation in epidermis.

Du H, Wang Y, Haensel D, Lee B, Dai X, Nie Q.

PLoS Comput Biol. 2018 Feb 26;14(2):e1006006. doi: 10.1371/journal.pcbi.1006006. eCollection 2018 Feb.


Ex Vivo Imaging and Genetic Manipulation of Mouse Hair Follicle Bulge Stem Cells.

Haensel D, McNeil MA, Dai X.

Methods Mol Biol. 2018 Feb 25. doi: 10.1007/7651_2018_136. [Epub ahead of print]


MiR-31 promotes mammary stem cell expansion and breast tumorigenesis by suppressing Wnt signaling antagonists.

Lv C, Li F, Li X, Tian Y, Zhang Y, Sheng X, Song Y, Meng Q, Yuan S, Luan L, Andl T, Feng X, Jiao B, Xu M, Plikus MV, Dai X, Lengner C, Cui W, Ren F, Shuai J, Millar SE, Yu Z.

Nat Commun. 2017 Oct 19;8(1):1036. doi: 10.1038/s41467-017-01059-5.


Inflammation: Memory beyond immunity.

Dai X, Medzhitov R.

Nature. 2017 Oct 26;550(7677):460-461. doi: 10.1038/nature24154. Epub 2017 Oct 18. No abstract available.


Epithelial-to-mesenchymal transition in cutaneous wound healing: Where we are and where we are heading.

Haensel D, Dai X.

Dev Dyn. 2018 Mar;247(3):473-480. doi: 10.1002/dvdy.24561. Epub 2017 Sep 5. Review.


Overexpression of Transcription Factor Ovol2 in Epidermal Progenitor Cells Results in Skin Blistering.

Lee B, Watanabe K, Haensel D, Sui JY, Dai X.

J Invest Dermatol. 2017 Aug;137(8):1805-1808. doi: 10.1016/j.jid.2017.02.985. Epub 2017 Apr 27. No abstract available.


Lgr4 is crucial for skin carcinogenesis by regulating MEK/ERK and Wnt/β-catenin signaling pathways.

Xu P, Dang Y, Wang L, Liu X, Ren X, Gu J, Liu M, Dai X, Ye X.

Cancer Lett. 2016 Dec 28;383(2):161-170. doi: 10.1016/j.canlet.2016.09.005. Epub 2016 Sep 30.


An Ovol2-Zeb1 Mutual Inhibitory Circuit Governs Bidirectional and Multi-step Transition between Epithelial and Mesenchymal States.

Hong T, Watanabe K, Ta CH, Villarreal-Ponce A, Nie Q, Dai X.

PLoS Comput Biol. 2015 Nov 10;11(11):e1004569. doi: 10.1371/journal.pcbi.1004569. eCollection 2015 Nov.


Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.

Li Q, Li Y, Gu B, Fang L, Zhou P, Bao S, Huang L, Dai X.

J Biol Chem. 2015 Aug 28;290(35):21553-67. doi: 10.1074/jbc.M115.639419. Epub 2015 Jul 13.


Computational modelling of epidermal stratification highlights the importance of asymmetric cell division for predictable and robust layer formation.

Gord A, Holmes WR, Dai X, Nie Q.

J R Soc Interface. 2014 Oct 6;11(99). pii: 20140631. doi: 10.1098/rsif.2014.0631.


The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.

Salmans ML, Yu Z, Watanabe K, Cam E, Sun P, Smyth P, Dai X, Andersen B.

PLoS Genet. 2014 Jul 31;10(7):e1004520. doi: 10.1371/journal.pgen.1004520. eCollection 2014 Jul.


Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia.

Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10215-20. doi: 10.1073/pnas.1311395111. Epub 2014 Jun 30.


Mammary morphogenesis and regeneration require the inhibition of EMT at terminal end buds by Ovol2 transcriptional repressor.

Watanabe K, Villarreal-Ponce A, Sun P, Salmans ML, Fallahi M, Andersen B, Dai X.

Dev Cell. 2014 Apr 14;29(1):59-74. doi: 10.1016/j.devcel.2014.03.006.


Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells.

Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X.

Dev Cell. 2014 Apr 14;29(1):47-58. doi: 10.1016/j.devcel.2014.03.005.


Integrative ChIP-seq/microarray analysis identifies a CTNNB1 target signature enriched in intestinal stem cells and colon cancer.

Watanabe K, Biesinger J, Salmans ML, Roberts BS, Arthur WT, Cleary M, Andersen B, Xie X, Dai X.

PLoS One. 2014 Mar 20;9(3):e92317. doi: 10.1371/journal.pone.0092317. eCollection 2014.


Transcriptional control of epidermal stem cells.

Lee B, Dai X.

Adv Exp Med Biol. 2013;786:157-73. doi: 10.1007/978-94-007-6621-1_9.


Chromatin effector Pygo2 mediates Wnt-notch crosstalk to suppress luminal/alveolar potential of mammary stem and basal cells.

Gu B, Watanabe K, Sun P, Fallahi M, Dai X.

Cell Stem Cell. 2013 Jul 3;13(1):48-61. doi: 10.1016/j.stem.2013.04.012. Epub 2013 May 16.


Analysis of gene expression in skin using laser capture microdissection.

Lee B, Geyfman M, Andersen B, Dai X.

Methods Mol Biol. 2013;989:109-17. doi: 10.1007/978-1-62703-330-5_10.


Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice.

Watanabe K, Fallahi M, Dai X.

Oncogene. 2014 Jan 30;33(5):632-42. doi: 10.1038/onc.2012.620. Epub 2013 Jan 21.


Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells.

Gu B, Watanabe K, Dai X.

Cell Cycle. 2012 Jan 1;11(1):79-87. doi: 10.4161/cc.11.1.18402. Epub 2012 Jan 1.

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