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Items: 1 to 20 of 66

1.

Pharmacologic Strategies for Assaying BMP Signaling Function.

Dinter T, Bocobo GA, Yu PB.

Methods Mol Biol. 2019;1891:221-233. doi: 10.1007/978-1-4939-8904-1_16.

PMID:
30414136
2.

Room With a View.

Yung LM, Yu PB.

Circ Cardiovasc Imaging. 2018 Aug;11(8):e008148. doi: 10.1161/CIRCIMAGING.118.008148. No abstract available.

PMID:
30354505
3.

Bone Morphogenetic Protein 9 is a Mechanistic Biomarker of Portopulmonary Hypertension.

Nikolic I, Yung LM, Yang P, Malhotra R, Paskin-Flerlage SD, Dinter T, Bocobo GA, Tumelty KE, Faugno AJ, Troncone L, McNeil ME, Huang X, Coser KR, Lai CSC, Upton PD, Goumans MJ, Zamanian RT, Elliott CG, Lee A, Zheng W, Berasi SP, Huard C, Morrell NW, Chung RT, Channick RW, Roberts KE, Yu PB.

Am J Respir Crit Care Med. 2018 Oct 12. doi: 10.1164/rccm.201807-1236OC. [Epub ahead of print]

PMID:
30312106
4.

Discovery of 3-(4-sulfamoylnaphthyl)pyrazolo[1,5-a]pyrimidines as potent and selective ALK2 inhibitors.

Jiang JK, Huang X, Shamim K, Patel PR, Lee A, Wang AQ, Nguyen K, Tawa G, Cuny GD, Yu PB, Zheng W, Xu X, Sanderson P, Huang W.

Bioorg Med Chem Lett. 2018 Nov 1;28(20):3356-3362. doi: 10.1016/j.bmcl.2018.09.006. Epub 2018 Sep 6.

PMID:
30227946
5.

Finding the Target: In Silico and Genetic Screening for Mechanistically Novel Drugs in PAH.

Graham BB, Yu PB.

Am J Respir Crit Care Med. 2018 Aug 21. doi: 10.1164/rccm.201808-1427ED. [Epub ahead of print] No abstract available.

PMID:
30130137
6.

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension.

Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA.

Sci Transl Med. 2018 Jun 13;10(445). pii: eaap7294. doi: 10.1126/scitranslmed.aap7294.

PMID:
29899023
7.

Career Development of Young Physician-Scientists in the Cardiovascular Sciences: Perspective and Advice From the Early Career Committee of the Cardiopulmonary, Critical Care, and Resuscitation Council of the American Heart Association.

Agarwal S, Spiekerkoetter E, Austin ED, de Jesus Perez V, Dezfulian C, Maron BA, Ryan JJ, Starks MA, Yu PB, Bonnet S, Perman SM.

Circ Res. 2018 May 11;122(10):1330-1333. doi: 10.1161/CIRCRESAHA.118.312999. No abstract available.

PMID:
29748361
8.

Update in Pulmonary Vascular Disease 2016 and 2017.

Brittain EL, Thennapan T, Maron BA, Chan SY, Austin ED, Spiekerkoetter E, Bogaard HJ, Guignabert C, Paulin R, Machado RF, Yu PB.

Am J Respir Crit Care Med. 2018 Jul 1;198(1):13-23. doi: 10.1164/rccm.201801-0062UP. No abstract available.

PMID:
29533671
9.

Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation".

Bagarova J, Vonner AJ, Armstrong KA, Börgermann J, Lai CSC, Deng DY, Beppu H, Alfano I, Filippakopoulos P, Morrell NW, Bullock AN, Knaus P, Mishina Y, Yu PB.

Mol Cell Biol. 2017 Sep 12;37(19). pii: e00284-17. doi: 10.1128/MCB.00284-17. Print 2017 Oct 1. No abstract available.

10.

Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification.

Agarwal S, Loder SJ, Breuler C, Li J, Cholok D, Brownley C, Peterson J, Hsieh HH, Drake J, Ranganathan K, Niknafs YS, Xiao W, Li S, Kumar R, Tompkins R, Longaker MT, Davis TA, Yu PB, Mishina Y, Levi B.

Mol Ther. 2017 Aug 2;25(8):1974-1987. doi: 10.1016/j.ymthe.2017.01.008. Epub 2017 Jul 15.

11.

The traumatic bone: trauma-induced heterotopic ossification.

Dey D, Wheatley BM, Cholok D, Agarwal S, Yu PB, Levi B, Davis TA.

Transl Res. 2017 Aug;186:95-111. doi: 10.1016/j.trsl.2017.06.004. Epub 2017 Jun 15. Review.

PMID:
28668522
12.

The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva.

Alessi Wolken DM, Idone V, Hatsell SJ, Yu PB, Economides AN.

Bone. 2018 Apr;109:210-217. doi: 10.1016/j.bone.2017.06.011. Epub 2017 Jun 16. Review.

13.

Macrophage migration inhibitory factor as a novel biomarker of portopulmonary hypertension.

DuBrock HM, Rodriguez-Lopez JM, LeVarge BL, Curry MP, VanderLaan PA, Zsengeller ZK, Pernicone E, Preston IR, Yu PB, Nikolic I, Xu D, Thadhani RI, Channick RN, Ananth Karumanchi S.

Pulm Circ. 2016 Dec;6(4):498-507. doi: 10.1086/688489.

14.

Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification.

Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, Economides AN, Yu PB.

Sci Transl Med. 2016 Nov 23;8(366):366ra163.

PMID:
27881824
15.

A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension.

Yung LM, Nikolic I, Paskin-Flerlage SD, Pearsall RS, Kumar R, Yu PB.

Am J Respir Crit Care Med. 2016 Nov 1;194(9):1140-1151.

16.

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation.

O'Rourke C, Shelton G, Hutcheson JD, Burke MF, Martyn T, Thayer TE, Shakartzi HR, Buswell MD, Tainsh RE, Yu B, Bagchi A, Rhee DK, Wu C, Derwall M, Buys ES, Yu PB, Bloch KD, Aikawa E, Bloch DB, Malhotra R.

J Vis Exp. 2016 May 31;(111). doi: 10.3791/54017.

17.

The Role of Bone Marrow-derived Cells in Pulmonary Arterial Hypertension. What Lies Beneath?

Nikolic I, Yu PB.

Am J Respir Crit Care Med. 2016 Apr 15;193(8):822-4. doi: 10.1164/rccm.201511-2293ED. No abstract available.

18.

Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.

Aghamohammadzadeh R, Zhang YY, Stephens TE, Arons E, Zaman P, Polach KJ, Matar M, Yung LM, Yu PB, Bowman FP, Opotowsky AR, Waxman AB, Loscalzo J, Leopold JA, Maron BA.

FASEB J. 2016 Jul;30(7):2511-27. doi: 10.1096/fj.201500042. Epub 2016 Mar 22.

19.

Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage.

Szulcek R, Happé CM, Rol N, Fontijn RD, Dickhoff C, Hartemink KJ, Grünberg K, Tu L, Timens W, Nossent GD, Paul MA, Leyen TA, Horrevoets AJ, de Man FS, Guignabert C, Yu PB, Vonk-Noordegraaf A, van Nieuw Amerongen GP, Bogaard HJ.

Am J Respir Crit Care Med. 2016 Jun 15;193(12):1410-20. doi: 10.1164/rccm.201506-1231OC.

PMID:
26760925
20.

Contributions of muscle-resident progenitor cells to homeostasis and disease.

Dey D, Goldhamer DJ, Yu PB.

Curr Mol Biol Rep. 2015 Dec;1(4):175-188. doi: 10.1007/s40610-015-0025-z. Epub 2015 Oct 10.

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