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Items: 1 to 20 of 31

1.

Traumatic injury induces stress granule formation and enhances motor dysfunctions in ALS/FTD models.

Anderson EN, Gochenaur L, Singh A, Grant R, Patel K, Watkins S, Wu JY, Pandey UB.

Hum Mol Genet. 2018 Apr 15;27(8):1366-1381. doi: 10.1093/hmg/ddy047.

PMID:
29432563
2.

TDP-43 regulates cancer-associated microRNAs.

Chen X, Fan Z, McGee W, Chen M, Kong R, Wen P, Xiao T, Chen X, Liu J, Zhu L, Chen R, Wu JY.

Protein Cell. 2017 Sep 26. doi: 10.1007/s13238-017-0480-9. [Epub ahead of print]

PMID:
28952053
3.

Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.

Wheeler E, Leong A, Liu CT, Hivert MF, Strawbridge RJ, Podmore C, Li M, Yao J, Sim X, Hong J, Chu AY, Zhang W, Wang X, Chen P, Maruthur NM, Porneala BC, Sharp SJ, Jia Y, Kabagambe EK, Chang LC, Chen WM, Elks CE, Evans DS, Fan Q, Giulianini F, Go MJ, Hottenga JJ, Hu Y, Jackson AU, Kanoni S, Kim YJ, Kleber ME, Ladenvall C, Lecoeur C, Lim SH, Lu Y, Mahajan A, Marzi C, Nalls MA, Navarro P, Nolte IM, Rose LM, Rybin DV, Sanna S, Shi Y, Stram DO, Takeuchi F, Tan SP, van der Most PJ, Van Vliet-Ostaptchouk JV, Wong A, Yengo L, Zhao W, Goel A, Martinez Larrad MT, Radke D, Salo P, Tanaka T, van Iperen EPA, Abecasis G, Afaq S, Alizadeh BZ, Bertoni AG, Bonnefond A, Böttcher Y, Bottinger EP, Campbell H, Carlson OD, Chen CH, Cho YS, Garvey WT, Gieger C, Goodarzi MO, Grallert H, Hamsten A, Hartman CA, Herder C, Hsiung CA, Huang J, Igase M, Isono M, Katsuya T, Khor CC, Kiess W, Kohara K, Kovacs P, Lee J, Lee WJ, Lehne B, Li H, Liu J, Lobbens S, Luan J, Lyssenko V, Meitinger T, Miki T, Miljkovic I, Moon S, Mulas A, Müller G, Müller-Nurasyid M, Nagaraja R, Nauck M, Pankow JS, Polasek O, Prokopenko I, Ramos PS, Rasmussen-Torvik L, Rathmann W, Rich SS, Robertson NR, Roden M, Roussel R, Rudan I, Scott RA, Scott WR, Sennblad B, Siscovick DS, Strauch K, Sun L, Swertz M, Tajuddin SM, Taylor KD, Teo YY, Tham YC, Tönjes A, Wareham NJ, Willemsen G, Wilsgaard T, Hingorani AD; EPIC-CVD Consortium; EPIC-InterAct Consortium; Lifelines Cohort Study, Egan J, Ferrucci L, Hovingh GK, Jula A, Kivimaki M, Kumari M, Njølstad I, Palmer CNA, Serrano Ríos M, Stumvoll M, Watkins H, Aung T, Blüher M, Boehnke M, Boomsma DI, Bornstein SR, Chambers JC, Chasman DI, Chen YI, Chen YT, Cheng CY, Cucca F, de Geus EJC, Deloukas P, Evans MK, Fornage M, Friedlander Y, Froguel P, Groop L, Gross MD, Harris TB, Hayward C, Heng CK, Ingelsson E, Kato N, Kim BJ, Koh WP, Kooner JS, Körner A, Kuh D, Kuusisto J, Laakso M, Lin X, Liu Y, Loos RJF, Magnusson PKE, März W, McCarthy MI, Oldehinkel AJ, Ong KK, Pedersen NL, Pereira MA, Peters A, Ridker PM, Sabanayagam C, Sale M, Saleheen D, Saltevo J, Schwarz PE, Sheu WHH, Snieder H, Spector TD, Tabara Y, Tuomilehto J, van Dam RM, Wilson JG, Wilson JF, Wolffenbuttel BHR, Wong TY, Wu JY, Yuan JM, Zonderman AB, Soranzo N, Guo X, Roberts DJ, Florez JC, Sladek R, Dupuis J, Morris AP, Tai ES, Selvin E, Rotter JI, Langenberg C, Barroso I, Meigs JB.

PLoS Med. 2017 Sep 12;14(9):e1002383. doi: 10.1371/journal.pmed.1002383. eCollection 2017 Sep.

4.

Preparation of intact mitochondria using free-flow isoelectric focusing with post-pH gradient sample injection for morphological, functional and proteomics studies.

He YC, Kong FZ, Fan LY, Wu JY, Liu XP, Li J, Sun Y, Zhang Q, Yang Y, Wu XJ, Xiao H, Cao CX.

Anal Chim Acta. 2017 Aug 22;982:200-208. doi: 10.1016/j.aca.2017.06.007. Epub 2017 Jun 17.

PMID:
28734361
5.

PINK1 and Parkin are genetic modifiers for FUS-induced neurodegeneration.

Chen Y, Deng J, Wang P, Yang M, Chen X, Zhu L, Liu J, Lu B, Shen Y, Fushimi K, Xu Q, Wu JY.

Hum Mol Genet. 2016 Dec 1;25(23):5059-5068. doi: 10.1093/hmg/ddw310.

6.

A new method for quantifying mitochondrial axonal transport.

Chen M, Li Y, Yang M, Chen X, Chen Y, Yang F, Lu S, Yao S, Zhou T, Liu J, Zhu L, Du S, Wu JY.

Protein Cell. 2016 Nov;7(11):804-819. doi: 10.1007/s13238-016-0268-3. Epub 2016 May 25.

7.

Calcinosis is associated with digital ulcers and osteoporosis in patients with systemic sclerosis: A Scleroderma Clinical Trials Consortium study.

Valenzuela A, Baron M; Canadian Scleroderma Research Group, Herrick AL, Proudman S, Stevens W; Australian Scleroderma Interest Group, Rodriguez-Reyna TS, Vacca A, Medsger TA Jr, Hinchcliff M, Hsu V, Wu JY, Fiorentino D, Chung L.

Semin Arthritis Rheum. 2016 Dec;46(3):344-349. doi: 10.1016/j.semarthrit.2016.05.008. Epub 2016 Jun 2.

8.

Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism.

Yi F, Kong R, Ren J, Zhu L, Lou J, Wu JY, Feng W.

J Mol Biol. 2016 Jul 31;428(15):3043-57. doi: 10.1016/j.jmb.2016.06.014. Epub 2016 Jun 27.

9.

MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.

Zhang Y, Chen M, Qiu Z, Hu K, McGee W, Chen X, Liu J, Zhu L, Wu JY.

Protein Cell. 2016 Jul;7(7):489-500. doi: 10.1007/s13238-016-0272-7. Epub 2016 Jun 1.

10.

Autism, an area that needs public attention and investment.

Wu JY.

Sci China Life Sci. 2015 Oct;58(10):931-2. doi: 10.1007/s11427-015-4940-2. No abstract available.

PMID:
26490975
11.

FUS Interacts with HSP60 to Promote Mitochondrial Damage.

Deng J, Yang M, Chen Y, Chen X, Liu J, Sun S, Cheng H, Li Y, Bigio EH, Mesulam M, Xu Q, Du S, Fushimi K, Zhu L, Wu JY.

PLoS Genet. 2015 Sep 3;11(9):e1005357. doi: 10.1371/journal.pgen.1005357. eCollection 2015 Sep.

12.

CD146 acts as a novel receptor for netrin-1 in promoting angiogenesis and vascular development.

Tu T, Zhang C, Yan H, Luo Y, Kong R, Wen P, Ye Z, Chen J, Feng J, Liu F, Wu JY, Yan X.

Cell Res. 2015 Mar;25(3):275-87. doi: 10.1038/cr.2015.15. Epub 2015 Feb 6.

13.

Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation.

Xu Y, Sun Y, Ye H, Zhu L, Liu J, Wu X, Wang L, He T, Shen Y, Wu JY, Xu Q.

Cell Discov. 2015 Nov 10;1:15032. doi: 10.1038/celldisc.2015.32. eCollection 2015.

14.

USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration.

Huang Z, Wen P, Kong R, Cheng H, Zhang B, Quan C, Bian Z, Chen M, Zhang Z, Chen X, Du X, Liu J, Zhu L, Fushimi K, Hua D, Wu JY.

Int J Cancer. 2015 Apr 15;136(8):1792-802. doi: 10.1002/ijc.29226. Epub 2014 Sep 29.

15.

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution.

Zhu L, Xu M, Yang M, Yang Y, Li Y, Deng J, Ruan L, Liu J, Du S, Liu X, Feng W, Fushimi K, Bigio EH, Mesulam M, Wang C, Wu JY.

Hum Mol Genet. 2014 Dec 20;23(25):6863-77. doi: 10.1093/hmg/ddu409. Epub 2014 Aug 11.

16.

Axon guidance factor SLIT2 inhibits neural invasion and metastasis in pancreatic cancer.

Göhrig A, Detjen KM, Hilfenhaus G, Körner JL, Welzel M, Arsenic R, Schmuck R, Bahra M, Wu JY, Wiedenmann B, Fischer C.

Cancer Res. 2014 Mar 1;74(5):1529-40. doi: 10.1158/0008-5472.CAN-13-1012. Epub 2014 Jan 21.

17.

PSF suppresses tau exon 10 inclusion by interacting with a stem-loop structure downstream of exon 10.

Ray P, Kar A, Fushimi K, Havlioglu N, Chen X, Wu JY.

J Mol Neurosci. 2011 Nov;45(3):453-66. doi: 10.1007/s12031-011-9634-z. Epub 2011 Sep 1.

18.

RNA helicase p68 (DDX5) regulates tau exon 10 splicing by modulating a stem-loop structure at the 5' splice site.

Kar A, Fushimi K, Zhou X, Ray P, Shi C, Chen X, Liu Z, Chen S, Wu JY.

Mol Cell Biol. 2011 May;31(9):1812-21. doi: 10.1128/MCB.01149-10. Epub 2011 Feb 22.

19.

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy.

Fushimi K, Long C, Jayaram N, Chen X, Li L, Wu JY.

Protein Cell. 2011 Feb;2(2):141-9. doi: 10.1007/s13238-011-1014-5. Epub 2011 Feb 14.

20.

Progranulin promotes neurite outgrowth and neuronal differentiation by regulating GSK-3β.

Gao X, Joselin AP, Wang L, Kar A, Ray P, Bateman A, Goate AM, Wu JY.

Protein Cell. 2010 Jun;1(6):552-62. doi: 10.1007/s13238-010-0067-1. Epub 2010 Jul 7.

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