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Items: 1 to 20 of 27


Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis.

Patel AS, Song JW, Chu SG, Mizumura K, Osorio JC, Shi Y, El-Chemaly S, Lee CG, Rosas IO, Elias JA, Choi AM, Morse D.

PLoS One. 2015 Mar 18;10(3):e0121246. doi: 10.1371/journal.pone.0121246. eCollection 2015.


Transforming growth factor-β1 downregulates vascular endothelial growth factor-D expression in human lung fibroblasts via the Jun NH2-terminal kinase signaling pathway.

Cui Y, Osorio JC, Risquez C, Wang H, Shi Y, Gochuico BR, Morse D, Rosas IO, El-Chemaly S.

Mol Med. 2014 Mar 20;20:120-34. doi: 10.2119/molmed.2013.00123.


Tobacco smoke-induced lung fibrosis and emphysema.

Morse D, Rosas IO.

Annu Rev Physiol. 2014;76:493-513. doi: 10.1146/annurev-physiol-021113-170411. Epub 2013 Nov 18. Review.


Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-β receptor I internalization and inhibiting transforming growth factor-β1 signaling.

Shi Y, Gochuico BR, Yu G, Tang X, Osorio JC, Fernandez IE, Risquez CF, Patel AS, Shi Y, Wathelet MG, Goodwin AJ, Haspel JA, Ryter SW, Billings EM, Kaminski N, Morse D, Rosas IO.

Am J Respir Crit Care Med. 2013 Oct 1;188(7):831-41. doi: 10.1164/rccm.201303-0434OC.


The expanding role of biomarkers in the assessment of smoking-related parenchymal lung diseases.

Doyle TJ, Pinto-Plata V, Morse D, Celli BR, Rosas IO.

Chest. 2012 Oct;142(4):1027-1034. doi: 10.1378/chest.12-1540. Review.


Regulation and functional significance of autophagy in respiratory cell biology and disease.

Patel AS, Morse D, Choi AM.

Am J Respir Cell Mol Biol. 2013 Jan;48(1):1-9. doi: 10.1165/rcmb.2012-0282TR. Epub 2012 Sep 13. Review.


Autophagy in idiopathic pulmonary fibrosis.

Patel AS, Lin L, Geyer A, Haspel JA, An CH, Cao J, Rosas IO, Morse D.

PLoS One. 2012;7(7):e41394. doi: 10.1371/journal.pone.0041394. Epub 2012 Jul 18.


Retinoic acid-related orphan receptor-α is induced in the setting of DNA damage and promotes pulmonary emphysema.

Shi Y, Cao J, Gao J, Zheng L, Goodwin A, An CH, Patel A, Lee JS, Duncan SR, Kaminski N, Pandit KV, Rosas IO, Choi AM, Morse D.

Am J Respir Crit Care Med. 2012 Sep 1;186(5):412-9. doi: 10.1164/rccm.201111-2023OC. Epub 2012 Jun 28.


Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation.

Xu JF, Washko GR, Nakahira K, Hatabu H, Patel AS, Fernandez IE, Nishino M, Okajima Y, Yamashiro T, Ross JC, Estépar RS, Diaz AA, Li HP, Qu JM, Himes BE, Come CE, D'Aco K, Martinez FJ, Han MK, Lynch DA, Crapo JD, Morse D, Ryter SW, Silverman EK, Rosas IO, Choi AM, Hunninghake GM; COPDGene Investigators.

Am J Respir Crit Care Med. 2012 Mar 1;185(5):547-56. doi: 10.1164/rccm.201108-1574OC. Epub 2012 Jan 12.


Clinical problem-solving. Breathless.

Gavin MC, Morse D, Partridge AH, Levy BD, Loscalzo J.

N Engl J Med. 2012 Jan 5;366(1):75-81. doi: 10.1056/NEJMcps1011918. No abstract available.


Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.

Morse D, Lin L, Choi AM, Ryter SW.

Free Radic Biol Med. 2009 Jul 1;47(1):1-12. doi: 10.1016/j.freeradbiomed.2009.04.007. Epub 2009 Apr 9. Review.


Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosis.

Zheng L, Zhou Z, Lin L, Alber S, Watkins S, Kaminski N, Choi AM, Morse D.

Am J Respir Cell Mol Biol. 2009 Jul;41(1):85-92. doi: 10.1165/rcmb.2007-0401OC. Epub 2008 Dec 18.


Inhaled CO in the treatment of acute lung injury.

Morse D, Choi AM.

Am J Physiol Lung Cell Mol Physiol. 2008 Apr;294(4):L642-3. doi: 10.1152/ajplung.00054.2008. Epub 2008 Feb 8. No abstract available.


Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system.

Ryter SW, Kim HP, Nakahira K, Zuckerbraun BS, Morse D, Choi AM.

Antioxid Redox Signal. 2007 Dec;9(12):2157-73. Review.


Heat-shock proteins: new keys to the development of cytoprotective therapies.

Kim HP, Morse D, Choi AM.

Expert Opin Ther Targets. 2006 Oct;10(5):759-69. Review.


Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease.

Ryter SW, Morse D, Choi AM.

Am J Respir Cell Mol Biol. 2007 Feb;36(2):175-82. Epub 2006 Sep 15. Review.


Heme oxygenase-1: from bench to bedside.

Morse D, Choi AM.

Am J Respir Crit Care Med. 2005 Sep 15;172(6):660-70. Epub 2005 May 18. Review.


Carbon monoxide suppresses bleomycin-induced lung fibrosis.

Zhou Z, Song R, Fattman CL, Greenhill S, Alber S, Oury TD, Choi AM, Morse D.

Am J Pathol. 2005 Jan;166(1):27-37.


Carbon monoxide: to boldly go where NO has gone before.

Ryter SW, Morse D, Choi AM.

Sci STKE. 2004 Apr 20;2004(230):RE6. Review.


MKK3 mitogen-activated protein kinase pathway mediates carbon monoxide-induced protection against oxidant-induced lung injury.

Otterbein LE, Otterbein SL, Ifedigbo E, Liu F, Morse DE, Fearns C, Ulevitch RJ, Knickelbein R, Flavell RA, Choi AM.

Am J Pathol. 2003 Dec;163(6):2555-63.

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