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Items: 1 to 20 of 214

1.

Outcomes of non-anaplastic stage III and 'inoperable' Wilms tumour treated in the UKW3 trial.

Irtan S, Messahel B, Moroz V, Taylor RE, Grundy R, Kelsey A, Vujanic G, Pritchard-Jones K; Renal Tumours Committee of the Children's Cancer and Leukaemia Group (CCLG).

Radiother Oncol. 2019 Feb;131:1-7. doi: 10.1016/j.radonc.2018.10.026. Epub 2018 Dec 15.

PMID:
30773174
2.

Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymoma.

Rogers HA, Chapman R, Kings H, Allard J, Barron-Hastings J, Pajtler KW, Sill M, Pfister S, Grundy RG.

Oncotarget. 2018 Nov 23;9(92):36530-36541. doi: 10.18632/oncotarget.26370. eCollection 2018 Nov 23.

3.

Neurocognitive, academic and functional outcomes in survivors of infant ependymoma (UKCCSG CNS 9204).

Morrall MCHJ, Reed-Berendt R, Moss K, Stocks H, Houston AL, Siddell P, Picton S, Grundy R.

Childs Nerv Syst. 2019 Mar;35(3):411-420. doi: 10.1007/s00381-018-4015-3. Epub 2018 Dec 15.

PMID:
30554263
4.

Chemical modulation of autophagy as an adjunct to chemotherapy in childhood and adolescent brain tumors.

Servante J, Estranero J, Meijer L, Layfield R, Grundy R.

Oncotarget. 2018 Oct 16;9(81):35266-35277. doi: 10.18632/oncotarget.26186. eCollection 2018 Oct 16. Review.

5.

Electrical impedance tomography effectively used in a case of paediatric pulmonary Langerhans cell histiocytosis.

Davies P, Gates S, Grundy R.

BMJ Case Rep. 2018 Sep 5;2018. pii: bcr-2017-224040. doi: 10.1136/bcr-2017-224040.

PMID:
30185449
6.

Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours.

Bennett CD, Kohe SE, Gill SK, Davies NP, Wilson M, Storer LCD, Ritzmann T, Paine SML, Scott IS, Nicklaus-Wollenteit I, Tennant DA, Grundy RG, Peet AC.

Sci Rep. 2018 Aug 10;8(1):11992. doi: 10.1038/s41598-018-30342-8.

7.

Prospective multicentre evaluation and refinement of an analysis tool for magnetic resonance spectroscopy of childhood cerebellar tumours.

Manias KA, Harris LM, Davies NP, Natarajan K, MacPherson L, Foster K, Brundler MA, Hargrave DR, Payne GS, Leach MO, Morgan PS, Auer D, Jaspan T, Arvanitis TN, Grundy RG, Peet AC.

Pediatr Radiol. 2018 Oct;48(11):1630-1641. doi: 10.1007/s00247-018-4182-0. Epub 2018 Jul 30.

8.

Germline mutations and somatic inactivation of TRIM28 in Wilms tumour.

Halliday BJ, Fukuzawa R, Markie DM, Grundy RG, Ludgate JL, Black MA, Skeen JE, Weeks RJ, Catchpoole DR, Roberts AGK, Reeve AE, Morison IM.

PLoS Genet. 2018 Jun 18;14(6):e1007399. doi: 10.1371/journal.pgen.1007399. eCollection 2018 Jun.

9.

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.

Pajtler KW, Wen J, Sill M, Lin T, Orisme W, Tang B, Hübner JM, Ramaswamy V, Jia S, Dalton JD, Haupfear K, Rogers HA, Punchihewa C, Lee R, Easton J, Wu G, Ritzmann TA, Chapman R, Chavez L, Boop FA, Klimo P, Sabin ND, Ogg R, Mack SC, Freibaum BD, Kim HJ, Witt H, Jones DTW, Vo B, Gajjar A, Pounds S, Onar-Thomas A, Roussel MF, Zhang J, Taylor JP, Merchant TE, Grundy R, Tatevossian RG, Taylor MD, Pfister SM, Korshunov A, Kool M, Ellison DW.

Acta Neuropathol. 2018 Aug;136(2):211-226. doi: 10.1007/s00401-018-1877-0. Epub 2018 Jun 16.

PMID:
29909548
10.

Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target.

Apps JR, Carreno G, Gonzalez-Meljem JM, Haston S, Guiho R, Cooper JE, Manshaei S, Jani N, Hölsken A, Pettorini B, Beynon RJ, Simpson DM, Fraser HC, Hong Y, Hallang S, Stone TJ, Virasami A, Donson AM, Jones D, Aquilina K, Spoudeas H, Joshi AR, Grundy R, Storer LCD, Korbonits M, Hilton DA, Tossell K, Thavaraj S, Ungless MA, Gil J, Buslei R, Hankinson T, Hargrave D, Goding C, Andoniadou CL, Brogan P, Jacques TS, Williams HJ, Martinez-Barbera JP.

Acta Neuropathol. 2018 May;135(5):757-777. doi: 10.1007/s00401-018-1830-2. Epub 2018 Mar 14.

11.

Metabolite Levels in Paediatric Brain Tumours Correlate with Histological Features.

Orphanidou-Vlachou E, Kohe SE, Brundler MA, MacPherson L, Sun Y, Davies N, Wilson M, Pan X, Arvanitis TN, Grundy RG, Peet AC.

Pathobiology. 2018;85(3):157-168. doi: 10.1159/000458423. Epub 2018 Feb 10.

PMID:
29428932
12.

Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures.

Lourdusamy A, Luo LZ, Storer LC, Cohen KJ, Resar L, Grundy RG.

Oncotarget. 2017 Dec 14;8(70):115570-115581. doi: 10.18632/oncotarget.23311. eCollection 2017 Dec 29.

13.

Vascular stenosis in a child with visual pathway glioma treated with bevacizumab: a case report and review of literature.

Pilotto C, Beshlawi I, Thomas A, Grundy RG.

Childs Nerv Syst. 2018 Apr;34(4):781-785. doi: 10.1007/s00381-017-3676-7. Epub 2017 Dec 16.

PMID:
29249070
14.

Radiomics in paediatric neuro-oncology: A multicentre study on MRI texture analysis.

Fetit AE, Novak J, Rodriguez D, Auer DP, Clark CA, Grundy RG, Peet AC, Arvanitis TN.

NMR Biomed. 2018 Jan;31(1). doi: 10.1002/nbm.3781. Epub 2017 Oct 26.

PMID:
29073725
15.

Application of pattern recognition techniques for classification of pediatric brain tumors by in vivo 3T 1 H-MR spectroscopy-A multi-center study.

Zarinabad N, Abernethy LJ, Avula S, Davies NP, Rodriguez Gutierrez D, Jaspan T, MacPherson L, Mitra D, Rose HEL, Wilson M, Morgan PS, Bailey S, Pizer B, Arvanitis TN, Grundy RG, Auer DP, Peet A.

Magn Reson Med. 2018 Apr;79(4):2359-2366. doi: 10.1002/mrm.26837. Epub 2017 Aug 8.

16.

Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification.

Andreiuolo F, Le Teuff G, Bayar MA, Kilday JP, Pietsch T, von Bueren AO, Witt H, Korshunov A, Modena P, Pfister SM, Pagès M, Castel D, Giangaspero F, Chimelli L, Varlet P, Rutkowski S, Frappaz D, Massimino M, Grundy R, Grill J; SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents).

PLoS One. 2017 Jun 15;12(6):e0178351. doi: 10.1371/journal.pone.0178351. eCollection 2017.

17.

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.

Haque F, Varlet P, Puntonet J, Storer L, Bountali A, Rahman R, Grill J, Carcaboso AM, Jones C, Layfield R, Grundy RG.

Acta Neuropathol Commun. 2017 Jun 6;5(1):45. doi: 10.1186/s40478-017-0449-1.

18.

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

Veldhuijzen van Zanten SE, Baugh J, Chaney B, De Jongh D, Sanchez Aliaga E, Barkhof F, Noltes J, De Wolf R, Van Dijk J, Cannarozzo A, Damen-Korbijn CM, Lieverst JA, Colditz N, Hoffmann M, Warmuth-Metz M, Bison B, Jones DT, Sturm D, Gielen GH, Jones C, Hulleman E, Calmon R, Castel D, Varlet P, Giraud G, Slavc I, Van Gool S, Jacobs S, Jadrijevic-Cvrlje F, Sumerauer D, Nysom K, Pentikainen V, Kivivuori SM, Leblond P, Entz-Werle N, von Bueren AO, Kattamis A, Hargrave DR, Hauser P, Garami M, Thorarinsdottir HK, Pears J, Gandola L, Rutkauskiene G, Janssens GO, Torsvik IK, Perek-Polnik M, Gil-da-Costa MJ, Zheludkova O, Shats L, Deak L, Kitanovski L, Cruz O, Morales La Madrid A, Holm S, Gerber N, Kebudi R, Grundy R, Lopez-Aguilar E, Zapata-Tarres M, Emmerik J, Hayden T, Bailey S, Biassoni V, Massimino M, Grill J, Vandertop WP, Kaspers GJ, Fouladi M, Kramm CM, van Vuurden DG; members of the SIOPE DIPG Network.

J Neurooncol. 2017 Apr;132(2):255-266. doi: 10.1007/s11060-016-2363-y. Epub 2017 Jan 21.

19.

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, Planello AC, Zeller C, Barsyte-Lovejoy D, Lafay-Cousin L, Letourneau L, Bourgey M, Yu M, Gendoo DMA, Dzamba M, Barszczyk M, Medina T, Riemenschneider AN, Morrissy AS, Ra YS, Ramaswamy V, Remke M, Dunham CP, Yip S, Ng HK, Lu JQ, Mehta V, Albrecht S, Pimentel J, Chan JA, Somers GR, Faria CC, Roque L, Fouladi M, Hoffman LM, Moore AS, Wang Y, Choi SA, Hansford JR, Catchpoole D, Birks DK, Foreman NK, Strother D, Klekner A, Bognár L, Garami M, Hauser P, Hortobágyi T, Wilson B, Hukin J, Carret AS, Van Meter TE, Hwang EI, Gajjar A, Chiou SH, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheinemann K, Fleming AJ, Johnston DL, Michaud J, Zelcer S, Hammond R, Afzal S, Ramsay DA, Sirachainan N, Hongeng S, Larbcharoensub N, Grundy RG, Lulla RR, Fangusaro JR, Druker H, Bartels U, Grant R, Malkin D, McGlade CJ, Nicolaides T, Tihan T, Phillips J, Majewski J, Montpetit A, Bourque G, Bader GD, Reddy AT, Gillespie GY, Warmuth-Metz M, Rutkowski S, Tabori U, Lupien M, Brudno M, Schüller U, Pietsch T, Judkins AR, Hawkins CE, Bouffet E, Kim SK, Dirks PB, Taylor MD, Erdreich-Epstein A, Arrowsmith CH, De Carvalho DD, Rutka JT, Jabado N, Huang A.

Cancer Cell. 2016 Dec 12;30(6):891-908. doi: 10.1016/j.ccell.2016.11.003.

20.

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors.

Rogers HA, Estranero J, Gudka K, Grundy RG.

Oncotarget. 2017 Jan 10;8(2):2083-2095. doi: 10.18632/oncotarget.13781. Review.

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