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Items: 1 to 20 of 64

1.

Production and transplantation of bioengineered lung into a large-animal model.

Nichols JE, La Francesca S, Niles JA, Vega SP, Argueta LB, Frank L, Christiani DC, Pyles RB, Himes BE, Zhang R, Li S, Sakamoto J, Rhudy J, Hendricks G, Begarani F, Liu X, Patrikeev I, Pal R, Usheva E, Vargas G, Miller A, Woodson L, Wacher A, Grimaldo M, Weaver D, Mlcak R, Cortiella J.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaao3926. doi: 10.1126/scitranslmed.aao3926.

PMID:
30068570
2.

Disease-Specific Integration of Omics Data to Guide Functional Validation of Genetic Associations.

Shumyatcher M, Hong R, Levin J, Himes BE.

AMIA Annu Symp Proc. 2018 Apr 16;2017:1589-1596. eCollection 2017.

3.

Rapamycin-independent IGF2 expression in Tsc2-null mouse embryo fibroblasts and human lymphangioleiomyomatosis cells.

Himes BE, Obraztsova K, Lian L, Shumyatcher M, Rue R, Atochina-Vasserman EN, Hur SK, Bartolomei MS, Evans JF, Krymskaya VP.

PLoS One. 2018 May 14;13(5):e0197105. doi: 10.1371/journal.pone.0197105. eCollection 2018.

4.

Inclusion of Unstructured Clinical Text Improves Early Prediction of Death or Prolonged ICU Stay.

Weissman GE, Hubbard RA, Ungar LH, Harhay MO, Greene CS, Himes BE, Halpern SD.

Crit Care Med. 2018 Jul;46(7):1125-1132. doi: 10.1097/CCM.0000000000003148.

PMID:
29629986
5.

Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.

Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1552-1564. doi: 10.1164/rccm.201712-2529OC.

PMID:
29509491
6.

A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.

Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q.

J Allergy Clin Immunol. 2018 Jan 9. pii: S0091-6749(18)30023-X. doi: 10.1016/j.jaci.2017.11.040. [Epub ahead of print]

7.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL.

Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

8.

PDE8 Is Expressed in Human Airway Smooth Muscle and Selectively Regulates cAMP Signaling by β2-Adrenergic Receptors and Adenylyl Cyclase 6.

Johnstone TB, Smith KH, Koziol-White CJ, Li F, Kazarian AG, Corpuz ML, Shumyatcher M, Ehlert FJ, Himes BE, Panettieri RA Jr, Ostrom RS.

Am J Respir Cell Mol Biol. 2018 Apr;58(4):530-541. doi: 10.1165/rcmb.2017-0294OC.

9.

RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking.

Parker MM, Chase RP, Lamb A, Reyes A, Saferali A, Yun JH, Himes BE, Silverman EK, Hersh CP, Castaldi PJ.

BMC Med Genomics. 2017 Oct 6;10(1):58. doi: 10.1186/s12920-017-0295-9.

10.

TGF-β1 Evokes Human Airway Smooth Muscle Cell Shortening and Hyperresponsiveness via Smad3.

Ojiaku CA, Cao G, Zhu W, Yoo EJ, Shumyatcher M, Himes BE, An SS, Panettieri RA Jr.

Am J Respir Cell Mol Biol. 2018 May;58(5):575-584. doi: 10.1165/rcmb.2017-0247OC.

PMID:
28984468
11.

Enhancing Electronic Health Record Data with Geospatial Information.

Xie S, Greenblatt R, Levy MZ, Himes BE.

AMIA Jt Summits Transl Sci Proc. 2017 Jul 26;2017:123-132. eCollection 2017.

12.

Using omics approaches to understand pulmonary diseases.

Kan M, Shumyatcher M, Himes BE.

Respir Res. 2017 Aug 3;18(1):149. doi: 10.1186/s12931-017-0631-9. Review.

13.

Making progress toward understanding the genetic architecture of asthma in the most affected US ethnic group.

Himes BE, Ortega VE.

Eur Respir J. 2017 May 1;49(5). pii: 1700329. doi: 10.1183/13993003.00329-2017. Print 2017 May. No abstract available.

PMID:
28461304
14.

Integrated Stress Response Mediates Epithelial Injury in Mechanical Ventilation.

Dolinay T, Himes BE, Shumyatcher M, Lawrence GG, Margulies SS.

Am J Respir Cell Mol Biol. 2017 Aug;57(2):193-203. doi: 10.1165/rcmb.2016-0404OC.

15.

Gender-specific determinants of asthma among U.S. adults.

Greenblatt R, Mansour O, Zhao E, Ross M, Himes BE.

Asthma Res Pract. 2017 Jan 24;3:2. doi: 10.1186/s40733-017-0030-5. eCollection 2017.

16.

PTTG1IP and MAML3, novel genomewide association study genes for severity of hyperresponsiveness in adult asthma.

Nieuwenhuis MA, Vonk JM, Himes BE, Sarnowski C, Minelli C, Jarvis D, Bouzigon E, Nickle DC, Laviolette M, Sin D, Weiss ST, van den Berge M, Koppelman GH, Postma DS.

Allergy. 2017 May;72(5):792-801. doi: 10.1111/all.13062. Epub 2016 Nov 21.

17.

Inhibition of spleen tyrosine kinase attenuates IgE-mediated airway contraction and mediator release in human precision cut lung slices.

Koziol-White CJ, Jia Y, Baltus GA, Cooper PR, Zaller DM, Crackower MA, Sirkowski EE, Smock S, Northrup AB, Himes BE, Alves SE, Panettieri RA Jr.

Br J Pharmacol. 2016 Nov;173(21):3080-3087. doi: 10.1111/bph.13550. Epub 2016 Oct 5.

18.

Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner.

Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA Jr.

Br J Pharmacol. 2016 Sep;173(18):2726-38. doi: 10.1111/bph.13542. Epub 2016 Aug 3.

19.

Innovations in health information technologies for chronic pulmonary diseases.

Himes BE, Weitzman ER.

Respir Res. 2016 Apr 5;17:38. doi: 10.1186/s12931-016-0354-3. Review.

20.

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma.

Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA Jr, Weiss ST.

PLoS One. 2015 Jul 24;10(7):e0134057. doi: 10.1371/journal.pone.0134057. eCollection 2015.

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