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Items: 1 to 20 of 304


Multi-Omic Biological Age Estimation and Its Correlation With Wellness and Disease Phenotypes: A Longitudinal Study of 3,558 Individuals.

Earls JC, Rappaport N, Heath L, Wilmanski T, Magis AT, Schork NJ, Omenn GS, Lovejoy J, Hood L, Price ND.

J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(Supplement_1):S52-S60. doi: 10.1093/gerona/glz220.


Sex, obesity, diabetes, and exposure to particulate matter among patients with severe asthma: Scientific insights from a comparative analysis of open clinical data sources during a five-day hackathon.

Fecho K, Ahalt SC, Arunachalam S, Champion J, Chute CG, Davis S, Gersing K, Glusman G, Hadlock J, Lee J, Pfaff E, Robinson M, Sid E, Ta C, Xu H, Zhu R, Zhu Q, Peden DB; Biomedical Data Translator Consortium.

J Biomed Inform. 2019 Oct 30;100:103325. doi: 10.1016/j.jbi.2019.103325. [Epub ahead of print]


The Impact of Moyamoya Disease and RNF213 Mutations on the Spectrum of Plasma Protein and MicroRNA.

Lee MJ, Fallen S, Zhou Y, Baxter D, Scherler K, Kuo MF, Wang K.

J Clin Med. 2019 Oct 10;8(10). pii: E1648. doi: 10.3390/jcm8101648.


A systems approach to clinical oncology uses deep phenotyping to deliver personalized care.

Yurkovich JT, Tian Q, Price ND, Hood L.

Nat Rev Clin Oncol. 2019 Oct 16. doi: 10.1038/s41571-019-0273-6. [Epub ahead of print] Review.


Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease.

Zhou Y, Qin S, Sun M, Tang L, Yan X, Kim TK, Caballero J, Glusman G, Brunkow ME, Soloski MJ, Rebman AW, Scavarda C, Cooper D, Omenn GS, Moritz RL, Wormser GP, Price ND, Aucott JN, Hood L.

J Proteome Res. 2019 Nov 1. doi: 10.1021/acs.jproteome.9b00569. [Epub ahead of print]


Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder.

Dean KR, Hammamieh R, Mellon SH, Abu-Amara D, Flory JD, Guffanti G, Wang K, Daigle BJ Jr, Gautam A, Lee I, Yang R, Almli LM, Bersani FS, Chakraborty N, Donohue D, Kerley K, Kim TK, Laska E, Young Lee M, Lindqvist D, Lori A, Lu L, Misganaw B, Muhie S, Newman J, Price ND, Qin S, Reus VI, Siegel C, Somvanshi PR, Thakur GS, Zhou Y; PTSD Systems Biology Consortium, Hood L, Ressler KJ, Wolkowitz OM, Yehuda R, Jett M, Doyle FJ 3rd, Marmar C.

Mol Psychiatry. 2019 Sep 10. doi: 10.1038/s41380-019-0496-z. [Epub ahead of print]


Blood metabolome predicts gut microbiome α-diversity in humans.

Wilmanski T, Rappaport N, Earls JC, Magis AT, Manor O, Lovejoy J, Omenn GS, Hood L, Gibbons SM, Price ND.

Nat Biotechnol. 2019 Oct;37(10):1217-1228. doi: 10.1038/s41587-019-0233-9. Epub 2019 Sep 2.


Opportunities and Challenges in Interpreting and Sharing Personal Genomes.

Rubin IR, Glusman G.

Genes (Basel). 2019 Aug 25;10(9). pii: E643. doi: 10.3390/genes10090643.


MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labour.

Paquette AG, Shynlova O, Wu X, Kibschull M, Wang K, Price ND, Lye SJ.

J Cell Mol Med. 2019 Oct;23(10):6835-6845. doi: 10.1111/jcmm.14567. Epub 2019 Jul 24.


Mechanistic inferences on metabolic dysfunction in posttraumatic stress disorder from an integrated model and multiomic analysis: role of glucocorticoid receptor sensitivity.

Somvanshi PR, Mellon SH, Flory JD, Abu-Amara D; PTSD Systems Biology Consortium;, Wolkowitz OM, Yehuda R, Jett M, Hood L, Marmar C, Doyle FJ 3rd.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E879-E898. doi: 10.1152/ajpendo.00065.2019. Epub 2019 Jul 19.


Genome-scale metabolic model of the rat liver predicts effects of diet restriction.

Baloni P, Sangar V, Yurkovich JT, Robinson M, Taylor S, Karbowski CM, Hamadeh HK, He YD, Price ND.

Sci Rep. 2019 Jul 8;9(1):9807. doi: 10.1038/s41598-019-46245-1.


Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder.

Lee MY, Baxter D, Scherler K, Kim TK, Wu X, Abu-Amara D, Flory J, Yehuda R, Marmar C, Jett M, Lee I, Wang K, Hood L.

J Clin Med. 2019 Jul 3;8(7). pii: E963. doi: 10.3390/jcm8070963.


Blood Is a Window into Health and Disease.

Yurkovich JT, Hood L.

Clin Chem. 2019 Oct;65(10):1204-1206. doi: 10.1373/clinchem.2018.299065. Epub 2019 Jun 6. No abstract available.


Publisher Correction: Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.

Ngô HM, Zhou Y, Lorenzi H, Wang K, Kim TK, Zhou Y, El Bissati K, Mui E, Fraczek L, Rajagopala SV, Roberts CW, Henriquez FL, Montpetit A, Blackwell JM, Jamieson SE, Wheeler K, Begeman IJ, Naranjo-Galvis C, Alliey-Rodriguez N, Davis RG, Soroceanu L, Cobbs C, Steindler DA, Boyer K, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Withers S, Soteropoulos P, Hood L, McLeod R.

Sci Rep. 2019 May 28;9(1):8110. doi: 10.1038/s41598-019-44545-0.


A biological function based biomarker panel optimization process.

Lee MY, Kim TK, Walters KA, Wang K.

Sci Rep. 2019 May 14;9(1):7365. doi: 10.1038/s41598-019-43779-2.


Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection.

Walters KA, Zhu R, Welge M, Scherler K, Park JK, Rahil Z, Wang H, Auvil L, Bushell C, Lee MY, Baxter D, Bristol T, Rosas LA, Cervantes-Medina A, Czajkowski L, Han A, Memoli MJ, Taubenberger JK, Kash JC.

MBio. 2019 May 14;10(3). pii: e00760-19. doi: 10.1128/mBio.00760-19.


Clinical Data: Sources and Types, Regulatory Constraints, Applications.

Ahalt SC, Chute CG, Fecho K, Glusman G, Hadlock J, Taylor CO, Pfaff ER, Robinson PN, Solbrig H, Ta C, Tatonetti N, Weng C; Biomedical Data Translator Consortium.

Clin Transl Sci. 2019 Jul;12(4):329-333. doi: 10.1111/cts.12638. Epub 2019 May 9. No abstract available.


Extracellular Vesicle Encapsulated MicroRNAs in Patients with Type 2 Diabetes Are Affected by Metformin Treatment.

Ghai V, Kim TK, Etheridge A, Nielsen T, Hansen T, Pedersen O, Galas D, Wang K.

J Clin Med. 2019 May 7;8(5). pii: E617. doi: 10.3390/jcm8050617.


Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program.

Zubair N, Conomos MP, Hood L, Omenn GS, Price ND, Spring BJ, Magis AT, Lovejoy JC.

Sci Rep. 2019 May 2;9(1):6805. doi: 10.1038/s41598-019-43058-0.


Reproducible big data science: A case study in continuous FAIRness.

Madduri R, Chard K, D'Arcy M, Jung SC, Rodriguez A, Sulakhe D, Deutsch E, Funk C, Heavner B, Richards M, Shannon P, Glusman G, Price N, Kesselman C, Foster I.

PLoS One. 2019 Apr 11;14(4):e0213013. doi: 10.1371/journal.pone.0213013. eCollection 2019.

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