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Items: 1 to 20 of 49


A RAS-CaMKKβ-AMPKα2 pathway promotes senescence by licensing post-translational activation of C/EBPβ through a novel 3'UTR mechanism.

Basu SK, Gonit M, Salotti J, Chen J, Bhat A, Gorospe M, Viollet B, Claffey KP, Johnson PF.

Oncogene. 2018 Mar 22. doi: 10.1038/s41388-018-0190-7. [Epub ahead of print]


Nucleolin phosphorylation regulates PARN deadenylase activity during cellular stress response.

Zhang X, Xiao S, Rameau RD, Devany E, Nadeem Z, Caglar E, Ng K, Kleiman FE, Saxena A.

RNA Biol. 2018 Feb 1;15(2):251-260. doi: 10.1080/15476286.2017.1408764. Epub 2017 Dec 15.


Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells - A possible sign of endogenous neuroprotection failure.

Smedowski A, Liu X, Podracka L, Akhtar S, Trzeciecka A, Pietrucha-Dutczak M, Lewin-Kowalik J, Urtti A, Ruponen M, Kaarniranta K, Varjosalo M, Amadio M.

Biochim Biophys Acta. 2018 Jan;1864(1):296-306. doi: 10.1016/j.bbadis.2017.10.030. Epub 2017 Oct 28.


A comparative study of anti-aging properties and mechanism: resveratrol and caloric restriction.

Li J, Zhang CX, Liu YM, Chen KL, Chen G.

Oncotarget. 2017 Aug 9;8(39):65717-65729. doi: 10.18632/oncotarget.20084. eCollection 2017 Sep 12.


Long Noncoding RNA PURPL Suppresses Basal p53 Levels and Promotes Tumorigenicity in Colorectal Cancer.

Li XL, Subramanian M, Jones MF, Chaudhary R, Singh DK, Zong X, Gryder B, Sindri S, Mo M, Schetter A, Wen X, Parvathaneni S, Kazandjian D, Jenkins LM, Tang W, Elloumi F, Martindale JL, Huarte M, Zhu Y, Robles AI, Frier SM, Rigo F, Cam M, Ambs S, Sharma S, Harris CC, Dasso M, Prasanth KV, Lal A.

Cell Rep. 2017 Sep 5;20(10):2408-2423. doi: 10.1016/j.celrep.2017.08.041.


The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice.

van den Hoogenhof MMG, van der Made I, Beqqali A, de Groot NE, Damanafshan A, van Oort RJ, Pinto YM, Creemers EE.

PLoS One. 2017 Aug 29;12(8):e0184093. doi: 10.1371/journal.pone.0184093. eCollection 2017.


Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities.

Su SC, Lin CW, Liu YF, Fan WL, Chen MK, Yu CP, Yang WE, Su CW, Chuang CY, Li WH, Chung WH, Yang SF.

Theranostics. 2017 Feb 26;7(5):1088-1099. doi: 10.7150/thno.18551. eCollection 2017.


LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro.

Wamsley JJ, Issaeva N, An H, Lu X, Donehower LA, Yarbrough WG.

Cell Cycle. 2017 Jan 17;16(2):213-223. doi: 10.1080/15384101.2016.1261767. Epub 2016 Dec 27.


HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation.

Alfano L, Costa C, Caporaso A, Antonini D, Giordano A, Pentimalli F.

Oncotarget. 2016 Nov 22;7(47):78127-78139. doi: 10.18632/oncotarget.13002.


Genome-scale functional analysis of the human genes modulating p53 activity by regulating MDM2 expression in a p53-independent manner.

Kim DM, Choi SH, Yeom YI, Min SH, Kim IC.

Biochem Biophys Res Commun. 2016 Sep 16;478(2):976-81. doi: 10.1016/j.bbrc.2016.08.063. Epub 2016 Aug 11.


Progress on the relationship between miR-125 family and tumorigenesis.

Yin H, Sun Y, Wang X, Park J, Zhang Y, Li M, Yin J, Liu Q, Wei M.

Exp Cell Res. 2015 Dec 10;339(2):252-60. doi: 10.1016/j.yexcr.2015.09.015. Epub 2015 Sep 25. Review.


PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells.

Zhang X, Devany E, Murphy MR, Glazman G, Persaud M, Kleiman FE.

Nucleic Acids Res. 2015 Dec 15;43(22):10925-38. doi: 10.1093/nar/gkv959. Epub 2015 Sep 22.


B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo.

DeMicco A, Naradikian MS, Sindhava VJ, Yoon JH, Gorospe M, Wertheim GB, Cancro MP, Bassing CH.

J Immunol. 2015 Oct 1;195(7):3449-62. doi: 10.4049/jimmunol.1500512. Epub 2015 Aug 28.


7SL RNA represses p53 translation by competing with HuR.

Abdelmohsen K, Panda AC, Kang MJ, Guo R, Kim J, Grammatikakis I, Yoon JH, Dudekula DB, Noh JH, Yang X, Martindale JL, Gorospe M.

Nucleic Acids Res. 2014 Sep;42(15):10099-111. doi: 10.1093/nar/gku686. Epub 2014 Aug 14.


Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB.

Hashimoto M, Tsugawa T, Kawagishi H, Asai A, Sugimoto M.

Biochim Biophys Acta. 2014 Oct;1840(10):3079-87. doi: 10.1016/j.bbagen.2014.07.005. Epub 2014 Jul 10.


Cytoplasmic expression of HuR may be a valuable diagnostic tool for determining the potential for malignant transformation of oral verrucous borderline lesions.

Habiba U, Kitamura T, Yanagawa-Matsuda A, Hida K, Higashino F, Ohiro Y, Totsuka Y, Shindoh M.

Oncol Rep. 2014 Apr;31(4):1547-54. doi: 10.3892/or.2014.3017. Epub 2014 Feb 10.


The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins.

Krishnan N, Titus MA, Thapar R.

PLoS One. 2014 Jan 9;9(1):e85427. doi: 10.1371/journal.pone.0085427. eCollection 2014.


The PPARβ agonist L-165041 promotes VEGF mRNA stabilization in HPV18-harboring HeLa cells through a receptor-independent mechanism.

Roche E, Lascombe I, Bittard H, Mougin C, Fauconnet S.

Cell Signal. 2014 Feb;26(2):433-43. doi: 10.1016/j.cellsig.2013.10.006. Epub 2013 Oct 28.


HuR maintains a replicative life span by repressing the ARF tumor suppressor.

Kawagishi H, Hashimoto M, Nakamura H, Tsugawa T, Watanabe A, Kontoyiannis DL, Sugimoto M.

Mol Cell Biol. 2013 May;33(10):1886-900. doi: 10.1128/MCB.01277-12. Epub 2013 Mar 18.

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