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Items: 1 to 20 of 28


Systematic bioinformatic approaches reveal novel gene expression signatures associated with acquired resistance to EGFR targeted therapy in lung cancer.

Mojtabavi Naeini M, Tavassoli M, Ghaedi K.

Gene. 2018 Aug 15;667:62-69. doi: 10.1016/j.gene.2018.04.077. Epub 2018 May 11.


HuR, TTP, and miR-133b expression in NSCLC and their association with prognosis.

Qian L, Ji AH, Zhang WJ, Zhao N.

Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):430-442. doi: 10.26355/eurrev_201801_14192.


HuR facilitates cancer stemness of lung cancer cells via regulating miR-873/CDK3 and miR-125a-3p/CDK3 axis.

Zhang Y, Yang L, Ling C, Heng W.

Biotechnol Lett. 2018 Apr;40(4):623-631. doi: 10.1007/s10529-018-2512-9. Epub 2018 Jan 17.


Chemo-biologic combinatorial drug delivery using folate receptor-targeted dendrimer nanoparticles for lung cancer treatment.

Amreddy N, Babu A, Panneerselvam J, Srivastava A, Muralidharan R, Chen A, Zhao YD, Munshi A, Ramesh R.

Nanomedicine. 2018 Feb;14(2):373-384. doi: 10.1016/j.nano.2017.11.010. Epub 2017 Nov 16.


HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.

Muralidharan R, Mehta M, Ahmed R, Roy S, Xu L, Aubé J, Chen A, Zhao YD, Herman T, Ramesh R, Munshi A.

Sci Rep. 2017 Aug 30;7(1):9694. doi: 10.1038/s41598-017-07787-4.


Tumor-targeted Nanoparticle Delivery of HuR siRNA Inhibits Lung Tumor Growth In Vitro and In Vivo By Disrupting the Oncogenic Activity of the RNA-binding Protein HuR.

Muralidharan R, Babu A, Amreddy N, Srivastava A, Chen A, Zhao YD, Kompella UB, Munshi A, Ramesh R.

Mol Cancer Ther. 2017 Aug;16(8):1470-1486. doi: 10.1158/1535-7163.MCT-17-0134. Epub 2017 Jun 1.


Detrimental ELAVL-1/HuR-dependent GSK3β mRNA stabilization impairs resolution in acute respiratory distress syndrome.

Hoffman O, Burns N, Vadász I, Eltzschig HK, Edwards MG, Vohwinkel CU.

PLoS One. 2017 Feb 14;12(2):e0172116. doi: 10.1371/journal.pone.0172116. eCollection 2017. Erratum in: PLoS One. 2017 Apr 13;12 (4):e0176134.


Aryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure.

Rogers S, de Souza AR, Zago M, Iu M, Guerrina N, Gomez A, Matthews J, Baglole CJ.

Sci Rep. 2017 Jan 12;7:40539. doi: 10.1038/srep40539.


Data on isoaspartylation of neuronal ELAVL proteins.

Pulido MA, DerHartunian MK, Sehgal P, Laird-Offringa IA.

Data Brief. 2016 Nov 17;9:1052-1055. eCollection 2016 Dec.


Long Noncoding RNA MALAT1 Promotes Aggressive Pancreatic Cancer Proliferation and Metastasis via the Stimulation of Autophagy.

Li L, Chen H, Gao Y, Wang YW, Zhang GQ, Pan SH, Ji L, Kong R, Wang G, Jia YH, Bai XW, Sun B.

Mol Cancer Ther. 2016 Sep;15(9):2232-43. doi: 10.1158/1535-7163.MCT-16-0008. Epub 2016 Jul 1.


Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.

Muralidharan R, Babu A, Amreddy N, Basalingappa K, Mehta M, Chen A, Zhao YD, Kompella UB, Munshi A, Ramesh R.

J Nanobiotechnology. 2016 Jun 21;14(1):47. doi: 10.1186/s12951-016-0201-1.


MiR-31 Functions as a Tumor Suppressor in Lung Adenocarcinoma Mainly by Targeting HuR.

Xu H, Ma J, Zheng J, Wu J, Qu C, Sun F, Xu S.

Clin Lab. 2016;62(4):711-8.


HuR-targeted nanotherapy in combination with AMD3100 suppresses CXCR4 expression, cell growth, migration and invasion in lung cancer.

Muralidharan R, Panneerselvam J, Chen A, Zhao YD, Munshi A, Ramesh R.

Cancer Gene Ther. 2015 Dec;22(12):581-90. doi: 10.1038/cgt.2015.55. Epub 2015 Oct 23.


Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma.

Vigouroux C, Casse JM, Battaglia-Hsu SF, Brochin L, Luc A, Paris C, Lacomme S, Gueant JL, Vignaud JM, Gauchotte G.

Lung Cancer. 2015 Aug;89(2):189-96. doi: 10.1016/j.lungcan.2015.05.008. Epub 2015 May 16.


Gene expression profiles on predicting protein interaction network and exploring of new treatments for lung cancer.

Yang Z, Zheng R, Gao Y, Zhang Q.

Mol Biol Rep. 2014 Dec;41(12):8203-10. doi: 10.1007/s11033-014-3722-4. Epub 2014 Sep 10. Retraction in: Mol Biol Rep. 2015 Oct;42(10):1493.


TLR9 signaling repressed tumor suppressor miR-7 expression through up-regulation of HuR in human lung cancer cells.

Li YJ, Wang CH, Zhou Y, Liao ZY, Zhu SF, Hu Y, Chen C, Luo JM, Wen ZK, Xu L.

Cancer Cell Int. 2013 Sep 3;13(1):90. doi: 10.1186/1475-2867-13-90.


Hu/elav RNA-binding protein HuR regulates parathyroid hormone related peptide expression in human lung adenocarcinoma cells.

Lauriola L, Serini S, Granone P, Lanza P, Martini M, Calviello G, Ranelletti FO.

Histol Histopathol. 2013 Sep;28(9):1205-16. doi: 10.14670/HH-28.1205. Epub 2013 Apr 10.


Lapatinib-mediated cyclooxygenase-2 expression via epidermal growth factor receptor/HuR interaction enhances the aggressiveness of triple-negative breast cancer cells.

Hsia TC, Tu CY, Chen YJ, Wei YL, Yu MC, Hsu SC, Tsai SL, Chen WS, Yeh MH, Yen CJ, Yu YL, Huang TC, Huang CY, Hung MC, Huang WC.

Mol Pharmacol. 2013 Apr;83(4):857-69. doi: 10.1124/mol.112.082743. Epub 2013 Jan 25.


Triptolide inhibits COX-2 expression by regulating mRNA stability in TNF-α-treated A549 cells.

Sun L, Zhang S, Jiang Z, Huang X, Wang T, Huang X, Li H, Zhang L.

Biochem Biophys Res Commun. 2011 Dec 9;416(1-2):99-105. doi: 10.1016/j.bbrc.2011.11.004. Epub 2011 Nov 10.


The RNA-binding protein HuR stabilizes cytosolic phospholipase A2α mRNA under interleukin-1β treatment in non-small cell lung cancer A549 Cells.

Liao WL, Wang WC, Chang WC, Tseng JT.

J Biol Chem. 2011 Oct 14;286(41):35499-508. doi: 10.1074/jbc.M111.263582. Epub 2011 Aug 23.

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