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Items: 1 to 20 of 24


Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells.

Lin GL, Ting HJ, Tseng TC, Juang V, Lo YL.

PLoS One. 2017 Oct 2;12(10):e0185625. doi: 10.1371/journal.pone.0185625. eCollection 2017.


E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C.

Sang XB, Zong ZH, Wang LL, Wu DD, Chen S, Liu BL, Zhao Y.

Oncotarget. 2017 Feb 28;8(9):14777-14793. doi: 10.18632/oncotarget.14833.


Regulation of cyclin D1 by arsenic and microRNA inhibits adipogenesis.

Beezhold K, Klei LR, Barchowsky A.

Toxicol Lett. 2017 Jan 4;265:147-155. doi: 10.1016/j.toxlet.2016.12.002. Epub 2016 Dec 5.


Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration.

Muralidharan R, Babu A, Amreddy N, Basalingappa K, Mehta M, Chen A, Zhao YD, Kompella UB, Munshi A, Ramesh R.

J Nanobiotechnology. 2016 Jun 21;14(1):47. doi: 10.1186/s12951-016-0201-1.


Phosphorylation of eIF4E Confers Resistance to Cellular Stress and DNA-Damaging Agents through an Interaction with 4E-T: A Rationale for Novel Therapeutic Approaches.

Martínez A, Sesé M, Losa JH, Robichaud N, Sonenberg N, Aasen T, Ramón Y Cajal S.

PLoS One. 2015 Apr 29;10(4):e0123352. doi: 10.1371/journal.pone.0123352. eCollection 2015.


GAP-43 slows down cell cycle progression via sequences in its 3'UTR.

De Moliner K, Wolfson ML, Perrone-Bizzozero N, Adamo AM.

Arch Biochem Biophys. 2015 Apr 1;571:66-75. doi: 10.1016/ Epub 2015 Feb 24.


The cytoskeletal inhibitors latrunculin A and blebbistatin exert antitumorigenic properties in human hepatocellular carcinoma cells by interfering with intracellular HuR trafficking.

Doller A, Badawi A, Schmid T, Brauss T, Pleli T, zu Heringdorf DM, Piiper A, Pfeilschifter J, Eberhardt W.

Exp Cell Res. 2015 Jan 1;330(1):66-80. doi: 10.1016/j.yexcr.2014.09.010. Epub 2014 Sep 21.


The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins.

Krishnan N, Titus MA, Thapar R.

PLoS One. 2014 Jan 9;9(1):e85427. doi: 10.1371/journal.pone.0085427. eCollection 2014.


Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability.

Zhang J, Ouyang W, Li J, Zhang D, Yu Y, Wang Y, Li X, Huang C.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):218-24. doi: 10.1016/j.taap.2012.06.012. Epub 2012 Jun 28.


Human antigen R contributes to hepatic stellate cell activation and liver fibrosis.

Woodhoo A, Iruarrizaga-Lejarreta M, Beraza N, García-Rodríguez JL, Embade N, Fernández-Ramos D, Martínez-López N, Gutiérrez-De Juan V, Arteta B, Caballeria J, Lu SC, Mato JM, Varela-Rey M, Martínez-Chantar ML.

Hepatology. 2012 Nov;56(5):1870-82. doi: 10.1002/hep.25828. Epub 2012 Oct 9.


Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.

Frau M, Tomasi ML, Simile MM, Demartis MI, Salis F, Latte G, Calvisi DF, Seddaiu MA, Daino L, Feo CF, Brozzetti S, Solinas G, Yamashita S, Ushijima T, Feo F, Pascale RM.

Hepatology. 2012 Jul;56(1):165-75. doi: 10.1002/hep.25643. Epub 2012 Jun 5.


Knockdown of human antigen R reduces the growth and invasion of breast cancer cells in vitro and affects expression of cyclin D1 and MMP-9.

Yuan Z, Sanders AJ, Ye L, Wang Y, Jiang WG.

Oncol Rep. 2011 Jul;26(1):237-45. doi: 10.3892/or.2011.1271. Epub 2011 Apr 18.


Il-19 reduces VSMC activation by regulation of mRNA regulatory factor HuR and reduction of mRNA stability.

Cuneo AA, Herrick D, Autieri MV.

J Mol Cell Cardiol. 2010 Oct;49(4):647-54. doi: 10.1016/j.yjmcc.2010.04.016. Epub 2010 May 6.


Novel function and intracellular localization of methionine adenosyltransferase 2beta splicing variants.

Xia M, Chen Y, Wang LC, Zandi E, Yang H, Bemanian S, Martínez-Chantar ML, Mato JM, Lu SC.

J Biol Chem. 2010 Jun 25;285(26):20015-21. doi: 10.1074/jbc.M109.094821. Epub 2010 Apr 26.


HuR knockdown changes the oncogenic potential of oral cancer cells.

Kakuguchi W, Kitamura T, Kuroshima T, Ishikawa M, Kitagawa Y, Totsuka Y, Shindoh M, Higashino F.

Mol Cancer Res. 2010 Apr;8(4):520-8. doi: 10.1158/1541-7786.MCR-09-0367. Epub 2010 Mar 23.


Akt2-mediated phosphorylation of Pitx2 controls Ccnd1 mRNA decay during muscle cell differentiation.

Gherzi R, Trabucchi M, Ponassi M, Gallouzi IE, Rosenfeld MG, Briata P.

Cell Death Differ. 2010 Jun;17(6):975-83. doi: 10.1038/cdd.2009.194. Epub 2009 Dec 18.


Impaired liver regeneration in mice lacking glycine N-methyltransferase.

Varela-Rey M, Fernández-Ramos D, Martínez-López N, Embade N, Gómez-Santos L, Beraza N, Vázquez-Chantada M, Rodríguez J, Luka Z, Wagner C, Lu SC, Martínez-Chantar ML, Mato JM.

Hepatology. 2009 Aug;50(2):443-52. doi: 10.1002/hep.23033.


Evidence for LKB1/AMP-activated protein kinase/ endothelial nitric oxide synthase cascade regulated by hepatocyte growth factor, S-adenosylmethionine, and nitric oxide in hepatocyte proliferation.

Vázquez-Chantada M, Ariz U, Varela-Rey M, Embade N, Martínez-Lopez N, Fernández-Ramos D, Gómez-Santos L, Lamas S, Lu SC, Martínez-Chantar ML, Mato JM.

Hepatology. 2009 Feb;49(2):608-17. doi: 10.1002/hep.22660.


Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.

Topisirovic I, Siddiqui N, Orolicki S, Skrabanek LA, Tremblay M, Hoang T, Borden KL.

Mol Cell Biol. 2009 Mar;29(5):1152-62. doi: 10.1128/MCB.01532-08. Epub 2008 Dec 29.


[Aberrant regulation of mRNA 3' untranslated region in cancers and inflammation].

Nguyen-Chi M, Morello D.

Med Sci (Paris). 2008 Mar;24(3):290-6. doi: 10.1051/medsci/2008243290. Review. French.

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