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Items: 1 to 20 of 41


Long noncoding RNA OCC-1 suppresses cell growth through destabilizing HuR protein in colorectal cancer.

Lan Y, Xiao X, He Z, Luo Y, Wu C, Li L, Song X.

Nucleic Acids Res. 2018 Jun 20;46(11):5809-5821. doi: 10.1093/nar/gky214.


Inhibition of IRES-dependent translation of caspase-2 by HuR confers chemotherapeutic drug resistance in colon carcinoma cells.

Badawi A, Biyanee A, Nasrullah U, Winslow S, Schmid T, Pfeilschifter J, Eberhardt W.

Oncotarget. 2018 Apr 6;9(26):18367-18385. doi: 10.18632/oncotarget.24840. eCollection 2018 Apr 6.


Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.

Bowler E, Porazinski S, Uzor S, Thibault P, Durand M, Lapointe E, Rouschop KMA, Hancock J, Wilson I, Ladomery M.

BMC Cancer. 2018 Apr 2;18(1):355. doi: 10.1186/s12885-018-4227-7.


Studying the mechanism of PLAGL2 overexpression and its carcinogenic characteristics based on 3'-untranslated region in colorectal cancer.

Su C, Li D, Li N, Du Y, Yang C, Bai Y, Lin C, Li X, Zhang Y.

Int J Oncol. 2018 Mar 6. doi: 10.3892/ijo.2018.4305. [Epub ahead of print]


MiR-155-5p controls colon cancer cell migration via post-transcriptional regulation of Human Antigen R (HuR).

Al-Haidari A, Algaber A, Madhi R, Syk I, Thorlacius H.

Cancer Lett. 2018 May 1;421:145-151. doi: 10.1016/j.canlet.2018.02.026. Epub 2018 Feb 20.


Modulation of the mRNA-binding protein HuR as a novel reversal mechanism of epirubicin-triggered multidrug resistance in colorectal cancer cells.

Lin GL, Ting HJ, Tseng TC, Juang V, Lo YL.

PLoS One. 2017 Oct 2;12(10):e0185625. doi: 10.1371/journal.pone.0185625. eCollection 2017.


HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.

Lang M, Berry D, Passecker K, Mesteri I, Bhuju S, Ebner F, Sedlyarov V, Evstatiev R, Dammann K, Loy A, Kuzyk O, Kovarik P, Khare V, Beibel M, Roma G, Meisner-Kober N, Gasche C.

Cancer Res. 2017 May 1;77(9):2424-2438. doi: 10.1158/0008-5472.CAN-15-1726. Epub 2017 Feb 20.


CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype.

Lal S, Cheung EC, Zarei M, Preet R, Chand SN, Mambelli-Lisboa NC, Romeo C, Stout MC, Londin E, Goetz A, Lowder CY, Nevler A, Yeo CJ, Campbell PM, Winter JM, Dixon DA, Brody JR.

Mol Cancer Res. 2017 Jun;15(6):696-707. doi: 10.1158/1541-7786.MCR-16-0361. Epub 2017 Feb 27.


Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2.

Badawi A, Hehlgans S, Pfeilschifter J, Rödel F, Eberhardt W.

Cancer Lett. 2017 May 1;393:103-112. doi: 10.1016/j.canlet.2017.02.010. Epub 2017 Feb 20.


HuR Enhances Early Restitution of the Intestinal Epithelium by Increasing Cdc42 Translation.

Liu L, Zhuang R, Xiao L, Chung HK, Luo J, Turner DJ, Rao JN, Gorospe M, Wang JY.

Mol Cell Biol. 2017 Mar 17;37(7). pii: e00574-16. doi: 10.1128/MCB.00574-16. Print 2017 Apr 1.


Autotaxin Expression Is Regulated at the Post-transcriptional Level by the RNA-binding Proteins HuR and AUF1.

Sun S, Zhang X, Lyu L, Li X, Yao S, Zhang J.

J Biol Chem. 2016 Dec 9;291(50):25823-25836. Epub 2016 Oct 26.


Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis.

Blanco FF, Preet R, Aguado A, Vishwakarma V, Stevens LE, Vyas A, Padhye S, Xu L, Weir SJ, Anant S, Meisner-Kober N, Brody JR, Dixon DA.

Oncotarget. 2016 Nov 8;7(45):74043-74058. doi: 10.18632/oncotarget.12189.


Exploiting a novel miR-519c-HuR-ABCG2 regulatory pathway to overcome chemoresistance in colorectal cancer.

To KK, Leung WW, Ng SS.

Exp Cell Res. 2015 Nov 1;338(2):222-31. doi: 10.1016/j.yexcr.2015.09.011. Epub 2015 Sep 18.


NEDDylation in liver cancer: The regulation of the RNA binding protein Hu antigen R.

Fernández-Ramos D, Martínez-Chantar ML.

Pancreatology. 2015 Jul;15(4 Suppl):S49-54. doi: 10.1016/j.pan.2015.03.006. Epub 2015 Mar 20. Review.


Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor development.

Giammanco A, Blanc V, Montenegro G, Klos C, Xie Y, Kennedy S, Luo J, Chang SH, Hla T, Nalbantoglu I, Dharmarajan S, Davidson NO.

Cancer Res. 2014 Sep 15;74(18):5322-35. doi: 10.1158/0008-5472.CAN-14-0726. Epub 2014 Aug 1.


Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L.

Winkler C, Doller A, Imre G, Badawi A, Schmid T, Schulz S, Steinmeyer N, Pfeilschifter J, Rajalingam K, Eberhardt W.

Cell Death Dis. 2014 Jul 10;5:e1321. doi: 10.1038/cddis.2014.279.


HuR regulates alternative splicing of the TRA2β gene in human colon cancer cells under oxidative stress.

Akaike Y, Masuda K, Kuwano Y, Nishida K, Kajita K, Kurokawa K, Satake Y, Shoda K, Imoto I, Rokutan K.

Mol Cell Biol. 2014 Aug;34(15):2857-73. doi: 10.1128/MCB.00333-14. Epub 2014 May 27.


Control of pro-angiogenic cytokine mRNA half-life in cancer: the role of AU-rich elements and associated proteins.

Griseri P, Pagès G.

J Interferon Cytokine Res. 2014 Apr;34(4):242-54. doi: 10.1089/jir.2013.0140. Review.


Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells.

Sharma A, Bhat AA, Krishnan M, Singh AB, Dhawan P.

Carcinogenesis. 2013 Nov;34(11):2610-21. doi: 10.1093/carcin/bgt207. Epub 2013 Jul 23.


Curcumin combined with turmerones, essential oil components of turmeric, abolishes inflammation-associated mouse colon carcinogenesis.

Murakami A, Furukawa I, Miyamoto S, Tanaka T, Ohigashi H.

Biofactors. 2013 Mar-Apr;39(2):221-32. doi: 10.1002/biof.1054. Epub 2012 Dec 11.


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